Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.36 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL246821 | 0.86 | CYP2C19 (0.42) | KMT2ASMN1; SMN2ALDH1A1KDM4ECYP2C19 | |
| SCHEMBL250446 | 0.85 | CYP2C19 (0.43) | KMT2ASMN1; SMN2ALDH1A1KDM4ECYP2C19 | |
| Hydrochloric Acid SCHEMBL44633 | 0.84 | MEN1 (0.39) | KMT2ASMN1; SMN2MEN1TP53MAPK1 | |
| Hydrochloric Acid SCHEMBL16714236 | 0.83 | ALDH1A1 (0.44) | KMT2ASMN1; SMN2MEN1TP53MAPK1 | |
| Bromide SCHEMBL5330548 | 0.83 | CYP2C19 (0.42) | KMT2ASMN1; SMN2ALDH1A1KDM4ECYP2C19 | |
| SCHEMBL6530596 | 0.82 | SMN1; SMN2 (0.45) | KMT2ASMN1; SMN2MEN1TP53MAPK1 | |
| Hydrochloric Acid SCHEMBL859875 | 0.80 | CYP2C19 (0.42) | KMT2ASMN1; SMN2CHRM2CHRNA7ALDH1A1 | |
| Hydrochloric Acid SCHEMBL21638 | 0.80 | ALDH1A1 (0.54) | KMT2ASMN1; SMN2MEN1TP53MAPK1 | |
| Hydrochloric Acid SCHEMBL11250018 | 0.80 | ALDH1A1 (0.54) | KMT2ASMN1; SMN2MEN1TP53MAPK1 | |
| Bromide SCHEMBL3261137 | 0.79 | ALDH1A1 (0.52) | KMT2ASMN1; SMN2MEN1TP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957395-B2 | Methods and systems for coating a medical device | ALLACCEM, INC. (US) | 2018-05-01 | — | — | US | disclosed |
| US-9212286-B2 | Methods and systems for coating a surface | ALLACCEM, INC. (US) | 2015-12-15 | — | — | US | disclosed |
| US-20130150809-A1 | METHODS AND SYSTEMS FOR COATING A MEDICAL DEVICE | ALLACCEM, INC. | 2013-06-13 | — | — | US | disclosed |
| US-8268381-B2 | Methods and systems for coating a medical device | ALLACCEM, INC. (US) | 2012-09-18 | — | — | US | disclosed |
| US-8067402-B2 | Methods and systems for coating an oral surface | ALLACCEM, INC. (US) | 2011-11-29 | — | — | US | disclosed |
| US-8067403-B2 | Methods and systems for preparing an antimicrobial composition | ALLACCEM, INC. (US) | 2011-11-29 | — | — | US | disclosed |
| US-20110015300-A1 | METHODS AND SYSTEMS FOR COATING A SURFACE | ALLACCEM, INC. | 2011-01-20 | — | — | US | disclosed |
| US-7713955-B2 | Applying to a surface one or more bridged polycyclic compounds comprising at least two cyclic groups defined in part by quaternary ammonium moieties; microbiocides; self-cleaning | ALLACCEM, INC. (US) | 2010-05-11 | — | — | US | disclosed |
| US-20080207581-A1 | Applying to a surface one or more bridged polycyclic compounds comprising at least two cyclic groups defined in part by quaternary ammonium moieties; microbiocides; self-cleaning | ALLACCEM, INC. | 2008-08-28 | — | — | US | disclosed |
| US-20080020127-A1 | Methods and systems for coating a medical device | ALLACCEM, INC. | 2008-01-24 | — | — | US | disclosed |
| US-20080021212-A1 | Methods and systems for preparing an antimicrobial composition | ALLACCEM, INC. | 2008-01-24 | — | — | US | disclosed |
| US-20070202342-A1 | Applying to an oral surface (teeth or gums)one or more bridged polycyclic compounds comprising at least two cyclic groups defined in part by quaternary ammonium moieties; microbiocides; self-cleaning; dentistry; bonding agents, resin cements, sealants | ALLACCEM, INC. | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021212-A1 | Methods and systems for preparing an antimicrobial composition | DNMT1, TET2, POLR1C | CHRM2 3283/4885ACHE 260/4885KMT2A 1094/4885 |
| US-20080207581-A1 | Applying to a surface one or more bridged polycyclic compounds comprising at least two cyclic groups defined in part by quaternary ammonium moieties; microbiocides; self-cleaning | DNMT1, TET2, CD14 | CHRM2 1871/4885ACHE 302/4885KMT2A 1123/4885 |
| US-20110015300-A1 | METHODS AND SYSTEMS FOR COATING A SURFACE | DNMT1, TET2, DNMT3A | CHRM2 1593/4885ACHE 147/4885KMT2A 522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.