Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC37A4 | O43826 | 3/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 10/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4463498 | 0.91 | RAB9A (0.40) | SLC37A4MEN1KMT2AKDM4EUSP2 | |
| SCHEMBL4455628 | 0.85 | ELANE (0.47) | SLC37A4EGFRPIM1ELANEMEN1 | |
| SCHEMBL2946624 | 0.83 | SLC37A4 (0.48) | SLC37A4EGFRPIM1ELANEMEN1 | |
| Anthraquinone SCHEMBL2948902 | 0.82 | SLC37A4 (0.48) | SLC37A4EGFRPIM1ELANEMEN1 | |
| SCHEMBL4463509 | 0.78 | MTNR1A (0.40) | SLC37A4ELANEMEN1KMT2AKDM4E | |
| SCHEMBL4453653 | 0.77 | SLC37A4 (0.40) | SLC37A4ELANEMEN1KMT2AKDM4E | |
| SCHEMBL4453646 | 0.75 | NPC1 (0.43) | MEN1KMT2AKDM4EUSP2ALDH1A1 | |
| Anthraquinone SCHEMBL2946623 | 0.73 | SLC37A4 (0.45) | SLC37A4MEN1KMT2AKDM4EUSP2 | |
| SCHEMBL2955955 | 0.73 | SLC37A4 (0.45) | SLC37A4MEN1KMT2AKDM4EUSP2 | |
| SCHEMBL4455603 | 0.73 | SLC37A4 (0.37) | SLC37A4KMT2AALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010474-A1 | METHOD FOR THE PRODUCTION OF MUMBAISTATIN DERIVATIVES | Sanofi-Aventis (FR) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007121822-A1 | METHOD FOR THE PRODUCTION OF MUMBAISTATIN DERIVATIVES | SANOFI-AVENTIS (DE) | 2007-11-01 | — | — | WO | disclosed |