Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455628 | 0.90 | ELANE (0.47) | SMN1; SMN2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4460906 | 0.85 | BCL2 (0.44) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4463498 | 0.84 | RAB9A (0.40) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL2957671 | 0.81 | MAPT (0.44) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL4463509 | 0.78 | MTNR1A (0.40) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL4453653 | 0.77 | SLC37A4 (0.40) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL4455117 | 0.75 | MEN1 (0.50) | SMN1; SMN2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4463478 | 0.75 | SLC37A4 (0.42) | SMN1; SMN2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL13742921 | 0.75 | MAPT (0.51) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL4455603 | 0.73 | SLC37A4 (0.37) | KMT2AALDH1A1THRBMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010474-A1 | METHOD FOR THE PRODUCTION OF MUMBAISTATIN DERIVATIVES | Sanofi-Aventis (FR) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007121822-A1 | METHOD FOR THE PRODUCTION OF MUMBAISTATIN DERIVATIVES | SANOFI-AVENTIS (DE) | 2007-11-01 | — | — | WO | disclosed |