Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7485074 | 0.86 | HTR1A (0.50) | HTR1ASLC6A4PARP1 | |
| SCHEMBL7479640 | 0.86 | HTR1A (0.50) | HTR1ASLC6A4PARP1 | |
| SCHEMBL12126135 | 0.84 | HTR1A (0.49) | HTR1ASLC6A4 | |
| SCHEMBL7486645 | 0.77 | HTR1A (0.48) | HTR1ASLC6A4PARP1 | |
| SCHEMBL11127581 | 0.72 | ESR1 (0.34) | HTR1ASLC6A4 | |
| SCHEMBL11124024 | 0.72 | PIN1 (0.40) | HTR1ASLC6A4 | |
| SCHEMBL7489213 | 0.72 | PARP1 (0.47) | HTR1ASLC6A4PARP1 | |
| SCHEMBL4344995 | 0.71 | PARP1 (0.46) | HTR1ASLC6A4PARP1 | |
| SCHEMBL13131963 | 0.70 | REN (0.38) | HTR1ASLC6A4 | |
| SCHEMBL6974185 | 0.69 | PARP1 (0.38) | HTR1ASLC6A4PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1992361-B1 | Remedy or preventive for digestive ulcer | ASTELLAS PHARMA INC (JP) | 2012-05-02 | — | — | EP | disclosed |
| EP-1783116-B1 | 2-PHENYLPYRIDINE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2009-08-26 | — | — | EP | disclosed |