Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 3/20 | 0.34 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4462239 | 0.60 | IGF1R (0.44) | IGF1RSLC5A7 | |
| SCHEMBL18639884 | 0.56 | MAOA (0.49) | — | |
| SCHEMBL15831688 | 0.56 | DRD2 (0.32) | — | |
| SCHEMBL15831689 | 0.54 | HCAR3 (0.30) | — | |
| SCHEMBL374287 | 0.54 | HRH3 (0.50) | SLC5A7 | |
| SCHEMBL7278456 | 0.54 | IGF1R (0.40) | IGF1RSLC5A7LRRK2 | |
| SCHEMBL16935387 | 0.54 | LRRK2 (0.39) | LRRK2 | |
| SCHEMBL19287832 | 0.53 | TGFBR1 (0.43) | SLC5A7 | |
| SCHEMBL19172586 | 0.53 | FPR2 (0.42) | LRRK2 | |
| SCHEMBL19172678 | 0.53 | LRRK2 (0.43) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009017838-A2 | COMBINATIONS OF JAK-2 INHIBITORS AND OTHER AGENTS | EXELIXIS, INC. (US) | 2009-02-05 | — | — | WO | disclosed |