SCHEMBL4465569

SCHEMBL4465569

Cc1cccc2c[c][nH]c12

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.39
ALDH1A1 P00352 3/20 0.39
DAO P14920 2/20 0.39
DDO Q99489 1/20 0.39
AHR P35869 1/20 0.38
KIF11 P52732 1/20 0.36
CYP1A2 P05177 4/20 0.35
AR P10275 2/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
TSHR P16473 1/20 0.33
ACHE P22303 1/20 0.33
NSD2 O96028 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3092122 0.73 PDE3B (0.35) ALDH1A1DAOPOLBTSHR
SCHEMBL442426 0.73 CA12 (0.44) DAODDOCA9
SCHEMBL4455876 0.73 AHR (0.48) CYP2A6DAOAHRCYP1A2AR
SCHEMBL9740425 0.73 CYP1A2 (0.39) ALDH1A1DAODDOCYP1A2CA1
SCHEMBL9740069 0.73 CYP1A2 (0.37) CYP2A6DAOCYP1A2POLBMAPT
SCHEMBL4477746 0.72 CA12 (0.41) CYP2A6ALDH1A1DAOCA1CA2
SCHEMBL9740115 0.72 MAPT (0.48) ALDH1A1CA2GAAMAPTTSHR
SCHEMBL4269594 0.70 NR3C1 (0.37) ARCA1CA2CA9GAA
SCHEMBL3071940 0.68 KIF11 (0.42) ALDH1A1KIF11POLBGAAMAPT
SCHEMBL4329097 0.68 ALDH1A1 (0.48) CYP2A6ALDH1A1KIF11CYP1A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114249533-A Preparation method of graphene oxide glaze modified polished ceramic tile 广西蒙娜丽莎新材料有限公司 2022-03-29 CN claimed
CN-111747981-A Transition metal compound and preparation method and application thereof 万华化学集团股份有限公司 2020-10-09 CN claimed
CN-115785093-A Polycyclic quinazolinone derivative and preparation method and application thereof 齐齐哈尔医学院 2023-03-14 CN disclosed
CN-115260079-A Synthetic method of isatin and derivatives thereof 湖北可赛化工有限公司 2022-11-01 CN disclosed
CN-114195553-B Preparation method of fibrous nano-alumina modified ceramic glazed tile 广西蒙娜丽莎新材料有限公司 2022-09-30 CN disclosed
CN-114249533-A Preparation method of graphene oxide glaze modified polished ceramic tile 广西蒙娜丽莎新材料有限公司 2022-03-29 CN disclosed
CN-114195553-A Preparation method of fibrous nano-alumina modified ceramic glazed tile 广西蒙娜丽莎新材料有限公司 2022-03-18 CN disclosed
CN-110041306-B 4-hydroxy-2-quinolone-N- (4-quinazolinone) -3-carboxamide derivatives 中国医学科学院药物研究所 2022-01-11 CN disclosed
CN-111777619-A 2-oxo spiro [ indoline-3, 4' -pyran ] ketone compound and synthesis method and application thereof 江苏师范大学 2020-10-16 CN disclosed
CN-111747981-A Transition metal compound and preparation method and application thereof 万华化学集团股份有限公司 2020-10-09 CN disclosed
CN-106800566-B Spirocyclic indolone compounds, preparation method, pharmaceutical composition and application 中国科学院上海有机化学研究所 2019-12-31 CN disclosed
EP-0896588-A1 CATALYST SYSTEM CONTAINING REACTION PRODUCT OF LIQUID SILICONE AND POLYAMINE Lyondell Petrochemical Company (US) 1999-02-17 EP disclosed
US-5756611-A REACTION PRODUCT OF AN ALCOHOL AND AN ORGANOMETALLIC COMPOUND; METALLOCENES LYONDELL PETROCHEMICAL COMPANY (US) 1998-05-26 US disclosed
US-5744417-A SILYLAMINE POLYMER AND ORGANOMETALLIC COMPOUND LYONDELL PETROCHEMICAL COMPANY (US) 1998-04-28 US disclosed
CN-1173186-A Aza-metallocene polymerization catalyst LYONDELL PETROCHEM (US) 1998-02-11 CN disclosed
WO-1997045459-A1 MODIFIED POLYSILOXANE CATALYSTS AND A METHOD OF USING THE SAME LYONDELL PETROCHEMICAL COMPANY (US) 1997-12-04 WO disclosed
WO-1997041157-A1 CATALYST SYSTEM CONTAINING REACTION PRODUCT OF LIQUID SILICONE AND POLYAMINE LYONDELL PETROCHEMICAL COMPANY (US) 1997-11-06 WO disclosed
EP-0799250-A2 AZAMETALLOCENE POLYMERIZATION CATALYSTS LYONDELL PETROCHEMICAL COMPANY (US) 1997-10-08 EP disclosed
US-5539124-A Polymerization catalysts based on transition metal complexes with ligands containing pyrrolyl ring OCCIDENTAL CHEMICAL CORPORATION (US) 1996-07-23 US disclosed
WO-1996020223-A2 AZAMETALLOCENE POLYMERIZATION CATALYSTS LYONDELL PETROCHEMICAL COMPANY (US) 1996-07-04 WO disclosed