Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | FYN | P06241 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455876 | 0.73 | AHR (0.48) | CYP1A2MEN1KMT2ALMNATSHR | |
| SCHEMBL442426 | 0.73 | CA12 (0.44) | CA12DAODDO | |
| SCHEMBL4465569 | 0.73 | CYP2A6 (0.39) | CYP1A2ALDH1A1CA2CA1TSHR | |
| SCHEMBL910230 | 0.71 | ALDH1A1 (0.41) | CYP1A2ALDH1A1MEN1KMT2AMCL1 | |
| SCHEMBL3071940 | 0.68 | KIF11 (0.42) | ALDH1A1MEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL4477746 | 0.68 | CA12 (0.41) | ALDH1A1MEN1KMT2AMCL1HPGD | |
| SCHEMBL4329097 | 0.68 | ALDH1A1 (0.48) | CYP1A2ALDH1A1MEN1KMT2AMCL1 | |
| SCHEMBL4269594 | 0.66 | NR3C1 (0.37) | APOBEC3GCA2CA1TSHRKDM4E | |
| SCHEMBL835944 | 0.66 | MAPT (0.53) | CYP1A2ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL109665 | 0.65 | AHR (0.56) | CYP1A2ALDH1A1MEN1KMT2AMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |