Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 8/20 | 0.68 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.47 |
| ▸ | PDE4A | P27815 | 4/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.47 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.46 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Theobromine SCHEMBL4018409 | 0.86 | CYP3A4 (0.66) | ADORA2BADORA2ACYP3A4PMP22MAPK1 | |
| Caffeine SCHEMBL462076 | 0.86 | ADORA2A (0.66) | ADORA2BADORA2ACYP3A4PMP22MAPK1 | |
| Theobromine SCHEMBL4024314 | 0.84 | MAPK1 (0.75) | ADORA2BADORA2ACYP3A4PMP22MAPK1 | |
| Theophylline Anhydrous SCHEMBL1655326 | 0.84 | MAPK1 (0.66) | ADORA2BADORA2ACYP3A4PMP22MAPK1 | |
| Theophylline Anhydrous SCHEMBL2328875 | 0.83 | ADORA2A (0.64) | ADORA2BADORA2ACYP3A4PMP22MAPK1 | |
| 3-Methylxanthine SCHEMBL1892894 | 0.83 | ADORA2B (0.77) | ADORA2BADORA2AMAPK1LMNAMAPT | |
| 1-Methylxanthine SCHEMBL10996 | 0.82 | ADORA2B (1.00) | ADORA2BADORA2ACYP3A4PMP22MAPK1 | |
| Theobromine SCHEMBL11599459 | 0.82 | CYP3A4 (1.00) | ADORA2BADORA2ACYP3A4PMP22MAPK1 | |
| Theobromine SCHEMBL3184 | 0.82 | CYP3A4 (1.00) | ADORA2BADORA2ACYP3A4PMP22MAPK1 | |
| Theobromine SCHEMBL1690622 | 0.82 | CYP3A4 (1.00) | ADORA2BADORA2ACYP3A4PMP22MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578401-A4 | COMPOSITIONS AND METHODS FOR PROMOTING WEIGHT LOSS, THERMOGENESIS, APPETITE SUPPRESSION, LEAN MUSCLE MASS, INCREASING METABOLISM AND BOOSTING ENERGY LEVELS, AND USE AS A DIETARY SUPPLEMENT IN MAMMALS | RTC RES & DEV LLC (US) | 2009-03-25 | — | — | EP | disclosed |
| EP-1578401-A2 | COMPOSITIONS AND METHODS FOR PROMOTING WEIGHT LOSS, THERMOGENESIS, APPETITE SUPPRESSION, LEAN MUSCLE MASS, INCREASING METABOLISM AND BOOSTING ENERGY LEVELS, AND USE AS A DIETARY SUPPLEMENT IN MAMMALS | RTC Research & Development, LLC. (US) | 2005-09-28 | — | — | EP | disclosed |
| US-20040077556-A1 | Compositions and methods for promoting weight loss, thermogenesis, appetite suppression, lean muscle mass, increasing metabolism and boosting energy levels, and use as a dietary supplement in mammals | RTC RESEARCH AND DEVELOPMENT, LLC | 2004-04-22 | — | — | US | disclosed |
| WO-2003090673-A2 | COMPOSITIONS AND METHODS FOR PROMOTING WEIGHT LOSS, THERMOGENESIS, APPETITE SUPPRESSION, LEAN MUSCLE MASS, INCREASING METABOLISM AND BOOSTING ENERGY LEVELS, AND USE AS A DIETARY SUPPLEMENT IN MAMMALS | RTC RESEARCH & DEVELOPMENT, LLC. (US) | 2003-11-06 | — | — | WO | disclosed |
| US-20020122800-A1 | Treatment of inflammatory oral diseases with a combination of inhibitors of TNF-alpha and immunosuppressive agents | SONIS STEPHEN T (US) | 2002-09-05 | — | — | US | disclosed |