Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.59 |
| ▸ | MAOB | P27338 | 3/20 | 0.59 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
| ▸ | GUSB | P08236 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281780 | 0.83 | MAOB (0.46) | MAOAMAOBHTR2AHTR2CHRH1 | |
| SCHEMBL7464605 | 0.83 | MAOA (0.64) | MAOAMAOBLTB4RLTB4R2CYP1A2 | |
| SCHEMBL10728083 | 0.81 | MAOB (0.42) | MAOAMAOBHTR2AHTR2CHRH1 | |
| SCHEMBL7509154 | 0.81 | KMT2A (0.42) | MAOAMAOBHTR2AHTR2CHRH1 | |
| SCHEMBL7509159 | 0.81 | TBXA2R (0.41) | MAOAMAOBHTR2AHTR2CHRH1 | |
| SCHEMBL7510366 | 0.81 | MAOA (0.43) | MAOAMAOBHTR2AHTR2CCYP1A2 | |
| SCHEMBL9527650 | 0.81 | NR3C2 (0.49) | MAOAMAOB | |
| SCHEMBL5400526 | 0.79 | HTR2A (0.44) | MAOAMAOBHTR2AHTR2CHRH1 | |
| SCHEMBL21996315 | 0.78 | MAOB (0.40) | MAOAMAOBHTR2AHTR2CHRH1 | |
| SCHEMBL10238629 | 0.78 | HTR2A (0.47) | MAOAMAOBHTR2AHTR2CHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048897-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION | COCRYSTAL PHARMA INC (US) | 2022-02-17 | — | — | US | disclosed |
| US-20200170254-A1 | OXADIAZOLINE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISMS | NIPPON SODA CO., LTD. (JP) | 2020-06-04 | — | — | US | disclosed |
| US-20200170254-A1 | OXADIAZOLINE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISMS | NIPPON SODA CO., LTD. (JP) | 2020-06-04 | — | — | US | disclosed |
| EP-3640244-A1 | OXADIAZOLINE COMPOUND AND PEST CONTROL AGENT | Nippon Soda Co., Ltd. (JP) | 2020-04-22 | — | — | EP | disclosed |
| WO-2009137531-A2 | COMPOSITIONS AND METHODS RELATED TO ACTION OF LOW DOSAGES OF DOXEPIN ON THE H1 AND 5-HT2A RECEPTORS | SOMAXON PHARMACEUTICALS, INC. (US) | 2009-11-12 | — | — | WO | disclosed |
| US-20040229899-A1 | Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR) | JEPPESEN LONE (DK) | 2004-11-18 | — | — | US | disclosed |
| US-6723731-B2 | 3-(4-(2-(5H-DIBENZO(A,D)CYCLOHEPTEN-5-YLOXY)-ETHOXYL-PHENYL)-2 -ETHOXY-PROPIONIC ACID ETHYL ESTER AS ANTIDIABETIC AGENTS AND TO TREAT OBESITY | NOVO NORDISK A/S (DK) | 2004-04-20 | — | — | US | disclosed |
| US-6602901-B2 | Antidiabetic agents, obesity | NOVO NORDISK A/S (DK) | 2003-08-05 | — | — | US | disclosed |
| US-6525086-B2 | Compounds, their preparation and use | NOVO NORDISK A/S (DK) | 2003-02-25 | — | — | US | disclosed |
| US-6407127-B2 | 3-(4-(2-(5H-DIBENZO(A,D)CYCLOHEPTEN-5-YLOXY)-ETHOXYL-PHENYL)-2 -ETHOXY-PROPIONIC ACID ETHYL ESTER AS ANTIDIABETIC AGENTS AND TO TREAT OBESITY | NOVO NORDISK A/S (DK) | 2002-06-18 | — | — | US | disclosed |
| US-5112817-A | Anticancer Drug Potentiators | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1992-05-12 | — | — | US | disclosed |
| US-4999363-A | Inhibit biosynthesis of thromboxane A2 | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-03-12 | — | — | US | disclosed |
| EP-0363212-A2 | Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-04-11 | — | — | EP | disclosed |
| US-4889858-A | ANTIHYPOXIC AGENTS, ANTICONVULSANTS, LIPID PEROXIDATION INHIBITORS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1989-12-26 | — | — | US | disclosed |
| EP-0345747-A2 | Tricyclic compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1989-12-13 | — | — | EP | disclosed |
| EP-0269755-A1 | DIBENZ b,e OXEPIN DERIVATIVE AND PHARMACEUTICAL CONTAINING THE SAME AS ACTIVE INGREDIENT | Dainippon Pharmaceutical Co., Ltd. (JP) | 1988-06-08 | — | — | EP | disclosed |
| EP-0069810-B1 | NOVEL DIBENZOXEPINS, THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THE USE OF DIBENZOXEPINS IN THE TREATMENT OF ALLERGIC CONDITIONS | MERCK & CO. INC. (US) | 1986-12-03 | — | — | EP | disclosed |
| EP-0069810-A1 | Novel dibenzoxepins, their preparation, compositions containing them and the use of dibenzoxepins in the treatment of allergic conditions | MERCK & CO. INC. (US) | 1983-01-19 | — | — | EP | disclosed |
| US-4282365-A | Dibenz[b,e]oxepin compounds | MERCK & CO., INC. (US) | 1981-08-04 | — | — | US | disclosed |
| US-4169205-A | BACTERICIDES; FUNGICIDES | E. R. SQUIBB & SONS, INC. (US) | 1979-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048897-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION | ACE, IRF3, MIF | MAOA 230/4885MAOB 154/4885HTR2A 4522/4885 |
| US-20200170254-A1 | OXADIAZOLINE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISMS | OXA1L, O60361, FOXO3 | MAOA 2356/4885MAOB 764/4885HTR2A 3337/4885 |
| US-20040229899-A1 | Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR) | PPARG, PPARA, PPARD | MAOA 1821/4885MAOB 1574/4885HTR2A 1365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.