Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 5/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 4/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530007 | 0.84 | NR3C2 (0.44) | NR3C2MAOBMAPK14HTR1APIN1 | |
| SCHEMBL16385859 | 0.83 | NR3C2 (0.43) | NR3C2MAPK14KDM4EALDH1A1GAA | |
| SCHEMBL4465669 | 0.81 | MAOA (0.59) | MAOAMAOB | |
| SCHEMBL7510366 | 0.81 | MAOA (0.43) | MAOAMAOBADRA2A | |
| SCHEMBL10444469 | 0.79 | NR3C2 (0.41) | NR3C2MAPK14 | |
| SCHEMBL11732410 | 0.78 | MAOA (0.68) | NR3C2MAOAMAOBADRA2A | |
| SCHEMBL21996315 | 0.75 | MAOB (0.40) | MAOAMAOBMAPK14ADRA2A | |
| SCHEMBL10446532 | 0.74 | HTR2C (0.40) | NR3C2MAPK14NOTUMKDM4EALDH1A1 | |
| SCHEMBL10559305 | 0.74 | DRD2 (0.42) | NR3C2MAOBMAPK14NOTUM | |
| SCHEMBL11281780 | 0.73 | MAOB (0.46) | MAOAMAOBMAPK14HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269755-B1 | DIBENZ b,e]OXEPIN DERIVATIVE AND PHARMACEUTICAL CONTAINING THE SAME AS ACTIVE INGREDIENT | DAINIPPON PHARMACEUTICAL CO (JP) | 1993-11-18 | — | — | EP | disclosed |
| US-4889858-A | ANTIHYPOXIC AGENTS, ANTICONVULSANTS, LIPID PEROXIDATION INHIBITORS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1989-12-26 | — | — | US | disclosed |
| EP-0269755-A1 | DIBENZ b,e OXEPIN DERIVATIVE AND PHARMACEUTICAL CONTAINING THE SAME AS ACTIVE INGREDIENT | Dainippon Pharmaceutical Co., Ltd. (JP) | 1988-06-08 | — | — | EP | disclosed |