Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | S100B | P04271 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15055409 | 1.00 | LTA4H (0.52) | LTA4HMAOBALDH1A1SMN1; SMN2ALOX12 | |
| SCHEMBL28443746 | 0.83 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2ALOX12TP53CYP3A4 | |
| SCHEMBL18947039 | 0.81 | MAOB (0.50) | MAOBALDH1A1TP53TSHRTRPA1 | |
| SCHEMBL12136378 | 0.81 | MAOB (0.50) | MAOBALDH1A1TP53TSHRTRPA1 | |
| SCHEMBL2342516 | 0.81 | MAOB (0.50) | MAOBALDH1A1TP53TSHRTRPA1 | |
| SCHEMBL7590594 | 0.80 | PTGS2 (0.44) | MAOBALDH1A1SMN1; SMN2ALOX12TSHR | |
| SCHEMBL4623866 | 0.76 | LTA4H (0.67) | LTA4HALDH1A1SMN1; SMN2ALOX12TP53 | |
| SCHEMBL12534124 | 0.76 | S100B (0.49) | ALDH1A1SMN1; SMN2TP53TSHRS100B | |
| SCHEMBL7763844 | 0.76 | S100B (0.49) | ALDH1A1SMN1; SMN2TP53TSHRS100B | |
| SCHEMBL17186587 | 0.76 | LTA4H (0.51) | LTA4HALDH1A1SMN1; SMN2ALOX12TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066601-A1 | HYDROSILYLATION | Agency for Science, Technology And Research (SG) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008039154-A1 | HYDROSILYLATION | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2008-04-03 | — | — | WO | disclosed |