Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1898019 | 1.00 | OPRM1 (0.38) | OPRM1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL1898021 | 1.00 | OPRM1 (0.38) | OPRM1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL657906 | 0.78 | OPRM1 (0.38) | OPRM1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL1898020 | 0.78 | OPRM1 (0.38) | OPRM1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL3964870 | 0.78 | OPRM1 (0.38) | OPRM1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL2529125 | 0.78 | OPRM1 (0.38) | OPRM1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL4466623 | 0.78 | KCNA5 (0.38) | OPRM1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL9065797 | 0.78 | OPRM1 (0.38) | OPRM1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL7757727 | 0.74 | OPRM1 (0.45) | OPRM1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL8498802 | 0.74 | KCNA5 (0.46) | OPRM1TRPM8TRPA1KCNA5TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009122408-A1 | STABLE C - (sup3) - CYCLOMETALATED PINCER COMPLEXES, THEIR PREPARATION AND USE AS CATALYSTS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD (IL) | 2009-10-08 | — | — | WO | disclosed |