Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1898020 | 1.00 | OPRM1 (0.38) | OPRM1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL2529125 | 1.00 | OPRM1 (0.38) | OPRM1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL3964870 | 1.00 | OPRM1 (0.38) | OPRM1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL11827649 | 0.79 | TRPM8 (0.39) | OPRM1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL1898019 | 0.78 | OPRM1 (0.38) | OPRM1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL657905 | 0.78 | OPRM1 (0.38) | OPRM1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL1898021 | 0.78 | OPRM1 (0.38) | OPRM1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL4466627 | 0.78 | OPRM1 (0.38) | OPRM1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL4466623 | 0.75 | KCNA5 (0.38) | OPRM1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL8498806 | 0.70 | TRPA1 (0.43) | OPRM1TRPM8TRPA1KCNA5TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579476-B1 | Cyanoacrylate adhesives with improved cured thermal properties | LOCTITE CORP (US) | 1996-01-24 | — | — | EP | disclosed |
| EP-0579476-A1 | Cyanoacrylate adhesives with improved cured thermal properties | LOCTITE CORPORATION (US) | 1994-01-19 | — | — | EP | disclosed |