Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8498802 | 0.80 | KCNA5 (0.46) | KCNA5TRPV1TRPM8TRPA1ALDH1A1 | |
| SCHEMBL7757727 | 0.79 | OPRM1 (0.45) | KCNA5TRPV1TRPM8TRPA1ALDH1A1 | |
| SCHEMBL4466627 | 0.78 | OPRM1 (0.38) | KCNA5TRPV1TRPM8TRPA1ALDH1A1 | |
| SCHEMBL1898019 | 0.78 | OPRM1 (0.38) | KCNA5TRPV1TRPM8TRPA1ALDH1A1 | |
| SCHEMBL1898021 | 0.78 | OPRM1 (0.38) | KCNA5TRPV1TRPM8TRPA1ALDH1A1 | |
| SCHEMBL2392586 | 0.77 | OPRM1 (0.45) | KCNA5TRPV1TRPM8TRPA1ALDH1A1 | |
| SCHEMBL10700915 | 0.76 | KCNA5 (0.50) | KCNA5TRPV1TRPM8TRPA1ALDH1A1 | |
| SCHEMBL2529125 | 0.75 | OPRM1 (0.38) | KCNA5TRPV1TRPM8TRPA1ALDH1A1 | |
| SCHEMBL3964870 | 0.75 | OPRM1 (0.38) | KCNA5TRPV1TRPM8TRPA1ALDH1A1 | |
| SCHEMBL9065797 | 0.75 | OPRM1 (0.38) | KCNA5TRPV1TRPM8TRPA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009122408-A1 | STABLE C - (sup3) - CYCLOMETALATED PINCER COMPLEXES, THEIR PREPARATION AND USE AS CATALYSTS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD (IL) | 2009-10-08 | — | — | WO | disclosed |