1400W

1400W

SCHEMBL4467

CC(=N)NCc1cccc(CN)c1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 4/20 0.49
NOS2 P35228 4/20 0.49
ALDH1A1 P00352 3/20 0.49
LOXL2 Q9Y4K0 3/20 0.49
NOS3 P29474 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
CYP3A4 P08684 1/20 0.49
NFKB1 P19838 1/20 0.49
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
TSHR P16473 1/20 0.47
CYP2C19 P33261 1/20 0.47
ENPP2 Q13822 1/20 0.46
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
PKM P14618 1/20 0.44
ALOX12 P18054 1/20 0.44
CFD P00746 1/20 0.43
KLKB1 P03952 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1400W SCHEMBL3115594 0.98 NOS1 (0.50) NOS1NOS2ALDH1A1LOXL2NOS3
1400W SCHEMBL27838006 0.98 NOS1 (0.50) NOS1NOS2ALDH1A1LOXL2NOS3
SCHEMBL7871418 0.91 ALDH1A1 (0.52) NOS1NOS2ALDH1A1SMN1; SMN2LMNA
Bromide SCHEMBL7871368 0.89 ALDH1A1 (0.50) NOS1NOS2ALDH1A1NOS3LMNA
SCHEMBL7865745 0.85 TPSAB1 (0.57) NOS1NOS2LOXL2NOS3CYP1A2
SCHEMBL31540904 0.84 LOXL2 (0.55) NOS1NOS2ALDH1A1LOXL2NOS3
Hydrochloric Acid SCHEMBL26979034 0.83 TPSAB1 (0.55) NOS1NOS2LOXL2NOS3CYP1A2
SCHEMBL8356748 0.83 LOXL2 (0.46) NOS1NOS2ALDH1A1LOXL2NOS3
SCHEMBL7874952 0.82 LOXL2 (0.49) NOS1NOS2ALDH1A1LOXL2NOS3
SCHEMBL31168314 0.82 CYP1A2 (0.56) NOS1NOS2ALDH1A1LOXL2NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2396 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122072092-A Electric ceramic furnace and power adjusting method 浙江绍兴苏泊尔生活电器有限公司 2026-05-22 CN claimed
EP-4744663-A2 SKIN COMPOSITION Eaderm Co., Ltd. (JP) 2026-05-20 EP claimed
CN-116364534-B Preparation method of GaN-based device ohmic contact 华润微电子(重庆)有限公司 2026-05-19 CN claimed
CN-116616595-B Control method and control device of cooking equipment, cooking equipment and storage medium 广东美的厨房电器制造有限公司 2026-05-15 CN claimed
EP-4709378-A1 COMPOUNDS FOR NOS-RELATED CANCERS AND METHODS OF USE Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. (IL) 2026-03-18 EP claimed
CN-121577414-A Lunar soil sintering simulation forming device and method 北京卫星制造厂有限公司 2026-02-27 CN claimed
EP-4659023-A1 METHOD OF PREDICTING SUCCESS OF A CANCER THERAPY Immusmol SAS (FR) 2025-12-10 EP claimed
US-20250276085-A1 SYNTHETIC MULTIDOMAIN PEPTIDE BIOMATERIALS THAT INHIBIT INDUCIBLE NITRIC OXIDE SYNTHASE WILLIAM MARSH RICE UNIVERSITY (US) 2025-09-04 US claimed
CN-120143313-A Super lens, preparation method thereof, camera module and electric equipment 华为技术有限公司 2025-06-13 CN claimed
CN-120121602-A Method for determining platinum content in solid super acid catalyst based on ICP-OES and application thereof 上海润和盛建设备科技有限公司 2025-06-10 CN claimed
WO-2005000229-A2 COMPOSITIONS AND METHODS FOR MODULATING S-NITROSOGLUTATHIONE REDUCTASE DUKE UNIVERSITY (US) 2005-01-06 WO claimed
US-20040235751-A1 Reduction of zinc-induced neurotoxic injury by blockade of nitric oxide synthesis FREDERICKSON CHRISTOPHER J (US) 2004-11-25 US claimed
WO-2004084827-A2 REDUCTION OF ZINC-INDUCED NEUROTOXIC INJURY BY BLOCKADE OF NITRIC OXIDE SYNTHESIS NEUROBIOTEX, INC. (US) 2004-10-07 WO claimed
EP-1432440-A2 ADJUVANTS FOR NUCLEIC ACID VACCINES GLAXO GROUP LIMITED (GB) 2004-06-30 EP claimed
WO-2003030935-A2 ADJUVANTS FOR NUCLEIC ACID VACCINES GLAXO GROUP LIMITED (GB) 2003-04-17 WO claimed
US-20020156129-A1 Method of treating pruritus and a pharmaceutical composition for the method IKEDA MOHANDO CO., LTD. (JP) 2002-10-24 US claimed
US-RE37438-E1 Acetamidine derivatives and their use as inhibitors for the nitric oxide synthase GLAXO WELLCOME INC. 2001-11-06 US claimed
US-5866612-A Acetamidine derivatives and their use as inhibitors for the nitric oxide synthase GLAXO WELLCOME INC. (US) 1999-02-02 US claimed
EP-0799191-A1 ACETAMIDINE DERIVATIVES AND THEIR USE AS INHIBITORS FOR THE NITRIC OXIDE SYNTHASE THE WELLCOME FOUNDATION LIMITED (GB) 1997-10-08 EP claimed
WO-1996019440-A1 ACETAMIDINE DERIVATIVES AND THEIR USE AS INHIBITORS FOR THE NITRIC OXIDE SYNTHASE THE WELLCOME FOUNDATION LIMITED (GB) 1996-06-27 WO claimed