Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 4/20 | 0.31 |
| ▸ | PLAA | Q9Y263 | 2/20 | 0.31 |
| ▸ | ALPG | P10696 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27295424 | 0.83 | KDM4E (0.33) | L3MBTL1 | |
| SCHEMBL3734570 | 0.76 | RAB9A (0.50) | CA12CA1CA2CA9 | |
| SCHEMBL24621515 | 0.74 | KDM4E (0.39) | L3MBTL1 | |
| SCHEMBL1178916 | 0.74 | ALPL (0.53) | CA12CA1CA2CA9ALPL | |
| SCHEMBL19359838 | 0.74 | EGLN3 (0.43) | — | |
| SCHEMBL14316067 | 0.73 | — | — | |
| SCHEMBL2428021 | 0.73 | — | — | |
| SCHEMBL3910931 | 0.70 | KDM5A (0.41) | — | |
| SCHEMBL12458257 | 0.70 | FGFR1 (0.32) | — | |
| SCHEMBL20370828 | 0.70 | CA12 (0.36) | CA12CA1CA2CA9IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7696210-B2 | Gonadotropin releasing hormone receptor antagonists | WYETH (US) | 2010-04-13 | — | — | US | disclosed |
| US-7696210-B2 | Gonadotropin releasing hormone receptor antagonists | WYETH (US) | 2010-04-13 | — | — | US | disclosed |
| US-7531542-B2 | Benzooxazole and benzothiazole antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2009-05-12 | — | — | US | disclosed |
| US-7531542-B2 | Benzooxazole and benzothiazole antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2009-05-12 | — | — | US | disclosed |
| US-20060264631-A1 | Benzooxazole and benzothiazole antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2006-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264631-A1 | Benzooxazole and benzothiazole antagonists of gonadotropin releasing hormone receptor | GNRHR, GHRHR, LHCGR | CA12 2433/4885CA1 1904/4885CA2 2306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.