SCHEMBL4467564

SCHEMBL4467564

CCOc1cc(O)ccc1C(C)(C)c1ccc(C(C)(C)c2ccc(O)cc2OCC)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.44
ESR2 Q92731 5/20 0.44
HSD17B10 Q99714 3/20 0.44
CYP3A4 P08684 2/20 0.44
HPGD P15428 2/20 0.44
AR P10275 1/20 0.44
TSHR P16473 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
HTR6 P50406 1/20 0.44
ESRRG P62508 1/20 0.44
SLC6A3 Q01959 1/20 0.44
ALDH1A1 P00352 5/20 0.39
LTA4H P09960 1/20 0.37
CALM1 P0DP23 2/20 0.36
MEN1 O00255 2/20 0.36
MAPT P10636 2/20 0.36
KMT2A Q03164 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6059481 0.91 LTA4H (0.40) ESR1ESR2HSD17B10CYP3A4HPGD
SCHEMBL4471833 0.89 ESR1 (0.49) ESR1ESR2HSD17B10CYP3A4HPGD
SCHEMBL11680067 0.84 ALDH1A1 (0.47) ESR1ESR2HSD17B10HPGDALDH1A1
SCHEMBL4462215 0.81 MAOB (0.52) ESR1ESR2HSD17B10CYP3A4HPGD
SCHEMBL957234 0.78 LTA4H (0.43) ESR1HSD17B10HPGDTSHRSLC6A2
SCHEMBL4465968 0.77 ESR1 (0.46) ESR1ESR2CYP3A4ALDH1A1LTA4H
SCHEMBL4463750 0.76 ESR1 (0.45) ESR1ESR2ALDH1A1LTA4HMEN1
SCHEMBL29458116 0.75 ESR1 (0.52) ESR1ESR2HSD17B10CYP3A4HPGD
SCHEMBL29587311 0.75 ESR1 (0.47) ESR1ESR2HSD17B10CYP3A4HPGD
SCHEMBL3026188 0.74 CALM1 (0.51) HSD17B10CYP3A4HPGDTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582355-B2 Optical unit using plastic lenses FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed
US-20060046065-A1 Optical unit using plastic lenses FUJI PHOTO FILM CO., LTD. 2006-03-02 US disclosed
US-6028161-A EXCELLENT TRANSPARENCY, HEAT RESISTANCE AND MECHANICAL PROPERTIES AND A LOW BIREFRINGENCE, MELT FLUIDITY AND MOLDABILITY; AN OPTICAL DISK, LENS AND AN OPTICAL FIBER MITSUI CHEMICALS, INC. (JP) 2000-02-22 US disclosed
EP-0926180-A2 A polycarbonate copolymer and applications thereof Mitsui Chemicals, Inc. (JP) 1999-06-30 EP disclosed