Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL6528423 | 0.90 | ESR1 (0.38) | KDM4EL3MBTL1ALDH1A1NPSR1HDAC3 | |
| SCHEMBL9717180 | 0.85 | AOC3 (0.43) | KDM4EL3MBTL1ALDH1A1AOC3TDP1 | |
| SCHEMBL6489577 | 0.83 | OPRM1 (0.39) | KDM4EL3MBTL1ALDH1A1AOC3KMT2A | |
| SCHEMBL9717165 | 0.80 | AOC3 (0.45) | KDM4EL3MBTL1ALDH1A1AOC3TDP1 | |
| SCHEMBL28986868 | 0.76 | ALDH1A1 (0.39) | KDM4EL3MBTL1ALDH1A1AOC3TDP1 | |
| Bromide SCHEMBL31050237 | 0.76 | CARM1 (0.42) | KDM4EL3MBTL1ALDH1A1AOC3TDP1 | |
| SCHEMBL6485740 | 0.76 | ESR1 (0.43) | KDM4EL3MBTL1ALDH1A1AOC3TDP1 | |
| SCHEMBL28784699 | 0.76 | MAPT (0.50) | ALDH1A1AOC3SMN1; SMN2TSHRMAPT | |
| SCHEMBL78451 | 0.75 | KDM4E (0.46) | KDM4EL3MBTL1ALDH1A1TDP1NPSR1 | |
| SCHEMBL453394 | 0.75 | KDM4E (0.55) | KDM4EL3MBTL1TDP1NPSR1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56128746-A | — | — | None | — | — | JP | disclosed |
| CN-109305932-A | A kind of preparation method of Silodosin intermediate | 阜阳欣奕华材料科技有限公司 | 2019-02-05 | — | — | CN | disclosed |
| EP-1991526-B1 | Tetracyclic indole derivatives as in vivo imaging agents and having peripheralbenzodiazepine receptor affinity (PBR) | HAMMERSMITH IMANET LTD (GB) | 2014-02-12 | — | — | EP | disclosed |
| EP-1991526-B1 | Tetracyclic indole derivatives as in vivo imaging agents and having peripheralbenzodiazepine receptor affinity (PBR) | HAMMERSMITH IMANET LTD (GB) | 2014-02-12 | — | — | EP | disclosed |
| US-8506932-B2 | Tetracyclic indole derivatives as in vivo imaging agents and having peripheralbenzodiazepine receptor affinity (PBR) | HAMMERSMITH IMANET LIMITED (GB) | 2013-08-13 | — | — | US | disclosed |
| US-8506932-B2 | Tetracyclic indole derivatives as in vivo imaging agents and having peripheralbenzodiazepine receptor affinity (PBR) | HAMMERSMITH IMANET LIMITED (GB) | 2013-08-13 | — | — | US | disclosed |
| US-8506932-B2 | Tetracyclic indole derivatives as in vivo imaging agents and having peripheralbenzodiazepine receptor affinity (PBR) | HAMMERSMITH IMANET LIMITED (GB) | 2013-08-13 | — | — | US | disclosed |
| CN-1945436-B | Lithographic printing plate precursor and lithographic printing method | FUJI PHOTO FILM CO LTD | 2012-07-04 | — | — | CN | disclosed |
| CN-1924703-B | Lithographic printing plate precursor, lithographic printing method, and novel cyanine dye | FUJI PHOTO FILM CO LTD | 2012-05-30 | — | — | CN | disclosed |
| CN-101111392-B | Original film for lithographic printing plate and lithographic printing method | FUJI PHOTO FILM CO LTD | 2010-05-12 | — | — | CN | disclosed |
| US-6180818-B1 | COMPOUND PROVIDING IMPROVED STORAGE STABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 2001-01-30 | — | — | US | disclosed |
| CN-1043766-C | Indole derivative and preparation and pharmaceutical using of same | TORAY INDUSTRIES (JP) | 1999-06-23 | — | — | CN | disclosed |
| CN-1092425-A | Indole derivatives, its manufacture method and medicinal use thereof | TORAY INDUSTRIES (JP) | 1994-09-21 | — | — | CN | disclosed |
| US-5086052-A | Antiarthritic, antiallergens, antiinflammatory agents; also for asthma and psoriasis | ABBOTT LABORATORIES (US) | 1992-02-04 | — | — | US | disclosed |
| US-4970210-A | ENZYME INHIBITORS | ABBOTT LABORATORIES (US) | 1990-11-13 | — | — | US | disclosed |
| EP-0299449-A2 | Pyridazinone, triazinone and oxapyridazinone lipoxygenase inhibiting compounds | ABBOTT LABORATORIES (US) | 1989-01-18 | — | — | EP | disclosed |
| US-4388393-A | ELECTROGRAPHY | RICOH CO., LTD. (JP) | 1983-06-14 | — | — | US | disclosed |
| JP-S56128746-A | NEW HYDRAZONE COMPOUND AND ITS PREPARATION | RICOH CO LTD | 1981-10-08 | — | — | JP | disclosed |
| US-4260770-A | Naphtholactam dyes | CIBA-GEIGY AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |
| US-3992421-A | ANTHRAQUINONE DYESTUFFS FOR BLUE DYEINGS OF POLYESTERS | AMERICAN COLOR & CHEMICAL CORPORATION (US) | 1976-11-16 | — | — | US | disclosed |