Sulfuric Acid

Sulfuric Acid

SCHEMBL6528423

NN(CCO)c1ccccc1.O=S(=O)(O)O

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.38
KDM4E B2RXH2 4/20 0.38
MAPT P10636 2/20 0.38
HSP90AA1 P07900 1/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
CYP3A4 P08684 1/20 0.38
GAA P10253 1/20 0.38
BLM P54132 1/20 0.38
GFER P55789 1/20 0.38
PMP22 Q01453 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
RORC P51449 1/20 0.36
TSHR P16473 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HPGD P15428 1/20 0.35
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4468683 0.90 KDM4E (0.43) KDM4EMAPTALDH1A1CYP3A4L3MBTL1
Sulfuric Acid SCHEMBL7800588 0.80 ALDH1A1 (0.42) ESR1KDM4EMAPTHSP90AA1ALDH1A1
Sulfuric Acid SCHEMBL6417780 0.78 ESR1 (0.49) ESR1ALDH1A1LMNAL3MBTL1TSHR
SCHEMBL8579363 0.78 ESR1 (0.35) ESR1KDM4EHSP90AA1L3MBTL1
SCHEMBL9717180 0.76 AOC3 (0.43) KDM4EMAPTALDH1A1CYP3A4L3MBTL1
Sulfuric Acid SCHEMBL28085258 0.74 TSHR (0.44) ESR1KDM4EMAPTHSP90AA1ALDH1A1
SCHEMBL6489577 0.74 OPRM1 (0.39) KDM4EALDH1A1L3MBTL1
Sulfuric Acid SCHEMBL9326021 0.74 TSHR (0.47) ESR1KDM4EMAPTHSP90AA1ALDH1A1
SCHEMBL23859846 0.73 RORC (0.46) ESR1KDM4EHSP90AA1L3MBTL1RORC
SCHEMBL9717165 0.72 AOC3 (0.45) KDM4EMAPTALDH1A1CYP3A4L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6933101-B2 Fluorine compound, surfactant, aqueous coating composition and silver halide photographic light-sensitive material using them FUJI PHOTO FILM CO., LTD. (JP) 2005-08-23 US disclosed
US-6806041-B2 PHOTO APPARATUS HAVING CYAN, RED, GREEN AND BLUE MULTILAYER COATINGS AND DETECTORS; PHOTOGRAPHIC FILMS; RECEIVERS FUJI PHOTO FILM CO., LTD. (JP) 2004-10-19 US disclosed
US-6686141-B2 SUPPORT HAVING LIGHT-SENSITIVE SILVER HALIDE EMULSION LAYER AND A NON-LIGHT-SENSITIVE LAYER; >60% OF THE PROJECTED AREA OF HALIDE GRAINS ARE TABULAR WITH AN AVERAGE ASPECT RATIO OF >5; PAG OF 4-8.5; STORAGE STABILITY; RAPID DEVELOPMENT FUJI PHOTO FILM CO., LTD. (JP) 2004-02-03 US disclosed
US-6114570-A IMPROVING THE STORABILITY OF A LATENT IMAGE AND AN EMULSIONS FUJI PHOTO FILM CO., LTD. (JP) 2000-09-05 US disclosed
US-5994546-A 4-(N,N-DIALKYLAMINO)ANILINE COMPOUNDS HAVING A 4-N SUBSTITUENT WHICH IS A POLYETHYLENEOXY GROUP AND WHICH FORMS A CONDENSED RING WITH BENZENE RING FUJI PHOTO FILM CO., LTD. (JP) 1999-11-30 US disclosed