Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | STS | P08842 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | CTSL | P07711 | 1/20 | 0.61 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.61 |
| ▸ | TUBB | P07437 | 1/20 | 0.61 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.61 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.61 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.61 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.61 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27399132 | 0.94 | ALDH1A1 (0.62) | ALDH1A1GAASTSKMT2AMEN1 | |
| SCHEMBL15264157 | 0.93 | CTSK (0.64) | ALDH1A1GAASTSKMT2AMEN1 | |
| SCHEMBL12276577 | 0.93 | STS (0.60) | ALDH1A1GAASTSKMT2AMEN1 | |
| SCHEMBL8811453 | 0.93 | CA1 (0.63) | ALDH1A1GAASTSKMT2AMEN1 | |
| SCHEMBL2303699 | 0.92 | STS (0.72) | ALDH1A1GAASTSKMT2AMEN1 | |
| SCHEMBL12857682 | 0.91 | KCNK3 (0.61) | ALDH1A1GAASTSKMT2AMEN1 | |
| SCHEMBL9854021 | 0.91 | HPGD (0.59) | ALDH1A1GAASTSKMT2AMEN1 | |
| SCHEMBL17285814 | 0.90 | SRD5A2 (0.62) | ALDH1A1GAASTSKMT2AMEN1 | |
| SCHEMBL15372973 | 0.90 | STS (0.57) | ALDH1A1GAASTSKMT2AMEN1 | |
| SCHEMBL12362759 | 0.90 | TUBB4A (0.72) | ALDH1A1GAAKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12017972-B2 | All-aromatic liquid-crystalline homo-polyimides with aromatic endgroups and crosslinked products therefrom | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2024-06-25 | — | — | US | disclosed |
| US-12017972-B2 | All-aromatic liquid-crystalline homo-polyimides with aromatic endgroups and crosslinked products therefrom | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2024-06-25 | — | — | US | disclosed |
| EP-2828241-B1 | COMPOSITIONS AND METHODS FOR INHIBITION OF CATHEPSINS | MATEON THERAPEUTICS INC (US) | 2018-09-12 | — | — | EP | disclosed |
| US-9873668-B2 | Compositions and methods for inhibition of cathepsins | MATEON THERAPEUTICS, INC. (US) | 2018-01-23 | — | — | US | disclosed |
| US-9873668-B2 | Compositions and methods for inhibition of cathepsins | MATEON THERAPEUTICS, INC. (US) | 2018-01-23 | — | — | US | disclosed |
| US-20160368869-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF CATHEPSINS | BAYLOR UNIVERSITY | 2016-12-22 | — | — | US | disclosed |
| US-20160368869-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF CATHEPSINS | BAYLOR UNIVERSITY | 2016-12-22 | — | — | US | disclosed |
| US-9458103-B2 | Compositions and methods for inhibition of cathepsins | MATEON THERAPEUTICS, INC. (US) | 2016-10-04 | — | — | US | disclosed |
| US-9458103-B2 | Compositions and methods for inhibition of cathepsins | MATEON THERAPEUTICS, INC. (US) | 2016-10-04 | — | — | US | disclosed |
| US-20150031915-A1 | Compositions and Methods for Inhibition of Cathepsins | MATEON THERAPEUTICS, INC. | 2015-01-29 | — | — | US | disclosed |
| US-20150031915-A1 | Compositions and Methods for Inhibition of Cathepsins | MATEON THERAPEUTICS, INC. | 2015-01-29 | — | — | US | disclosed |
| US-8877967-B2 | Compositions and methods for inhibition of cathepsins | OXIGENE, INC. (US) | 2014-11-04 | — | — | US | disclosed |
| US-8877967-B2 | Compositions and methods for inhibition of cathepsins | OXIGENE, INC. (US) | 2014-11-04 | — | — | US | disclosed |
| US-20130296605-A1 | Compositions and Methods for Inhibition of Cathepsins | MATEON THERAPEUTICS, INC. | 2013-11-07 | — | — | US | disclosed |
| US-20130296605-A1 | Compositions and Methods for Inhibition of Cathepsins | MATEON THERAPEUTICS, INC. | 2013-11-07 | — | — | US | disclosed |
| WO-2013142038-A2 | COMPOSITIONS AND METHODS FOR INHIBITION OF CATHEPSINS | OXIGENE, INC. (US) | 2013-09-26 | — | — | WO | disclosed |
| EP-0145834-A1 | Ion-selective compositions containing certain crown ethers | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-06-26 | — | — | EP | disclosed |
| US-4504368-A | ELECTRODES, CROWN ETHER | EASTMAN KODAK COMPANY (US) | 1985-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150031915-A1 | Compositions and Methods for Inhibition of Cathepsins | CTSF, CTSS, CTSZ | ALDH1A1 2276/4885GAA 17/4885STS 984/4885 |
| US-20130296605-A1 | Compositions and Methods for Inhibition of Cathepsins | CTSF, CTSS, CTSZ | ALDH1A1 2276/4885GAA 17/4885STS 984/4885 |
| US-20160368869-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF CATHEPSINS | CTSF, CTSS, CTSZ | ALDH1A1 2276/4885GAA 17/4885STS 984/4885 |
| US-12017972-B2 | All-aromatic liquid-crystalline homo-polyimides with aromatic endgroups and crosslinked products therefrom | TPR, AS3MT, ASF1A | ALDH1A1 2790/4885GAA 2119/4885STS 2647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.