Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.58 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | STS | P08842 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14159536 | 0.94 | HSD17B1 (0.64) | HSD17B1HSD17B2ALDH1A1LMNASRD5A2 | |
| SCHEMBL14030885 | 0.91 | MMP13 (0.56) | HSD17B1HSD17B2RAB9AGAASMN1; SMN2 | |
| SCHEMBL13374185 | 0.88 | MMP13 (0.60) | HSD17B1HSD17B2RAB9ANPC1TP53 | |
| SCHEMBL8901914 | 0.88 | MMP13 (0.60) | HSD17B1HSD17B2RAB9ANPC1TP53 | |
| SCHEMBL13026418 | 0.88 | MMP13 (0.60) | HSD17B1HSD17B2RAB9ANPC1TP53 | |
| SCHEMBL23771947 | 0.88 | HSD17B1 (0.58) | HSD17B1HSD17B2SMN1; SMN2ALDH1A1STS | |
| SCHEMBL14277023 | 0.87 | STS (0.48) | HSD17B1HSD17B2RAB9AGAANPC1 | |
| SCHEMBL16378706 | 0.87 | MTNR1B (0.62) | HSD17B1HSD17B2SMN1; SMN2STSSRD5A2 | |
| SCHEMBL3294529 | 0.87 | ACHE (0.72) | HSD17B1HSD17B2GAARELASMN1; SMN2 | |
| SCHEMBL30358265 | 0.87 | ACHE (0.72) | HSD17B1HSD17B2GAARELASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3426741-B1 | POLYARYLETHER KETONE COMPOSITIONS AND METHOD OF COATING A METAL SURFACE | SOLVAY SPECIALTY POLYMERS USA (US) | 2020-10-21 | — | — | EP | disclosed |
| US-10808143-B2 | Polyarylether ketone compositions and method of coating a metal surface | SOLVAY SPECIALTY POLYMERS USA, LLC (US) | 2020-10-20 | — | — | US | disclosed |
| US-20190031908-A1 | POLYARYLETHER KETONE COMPOSITIONS AND METHOD OF COATING A METAL SURFACE | SOLVAY USA INC. | 2019-01-31 | — | — | US | disclosed |
| WO-2017153290-A1 | POLYARYLETHER KETONE COMPOSITIONS AND METHOD OF COATING A METAL SURFACE | SOLVAY SPECIALTY POLYMERS USA, LLC (US) | 2017-09-14 | — | — | WO | disclosed |
| US-9109075-B2 | Cross-linked organic polymers for use as elastomers in high temperature applications | Delsper LP (US) | 2015-08-18 | — | — | US | disclosed |
| US-20140316079-A1 | Cross-Linked Organic Polymers For Use as Elastomers in High Temperature Applications | Delsper LP | 2014-10-23 | — | — | US | disclosed |