⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL791842 | 0.67 | CA2 (0.40) | — | |
| SCHEMBL5672168 | 0.67 | — | — | |
| SCHEMBL413067 | 0.67 | — | — | |
| SCHEMBL1202858 | 0.66 | RAB9A (0.36) | — | |
| SCHEMBL17103290 | 0.64 | — | — | |
| SCHEMBL13721022 | 0.62 | — | — | |
| SCHEMBL4923805 | 0.59 | — | — | |
| SCHEMBL12483221 | 0.59 | — | — | |
| SCHEMBL394820 | 0.59 | — | — | |
| Water SCHEMBL9340500 | 0.57 | LOXL2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240034737-A1 | Heterocyclic Derivatives as P2X7 Receptor Antagonists | BREYE THERAPEUTICS APS (DK) | 2024-02-01 | — | — | US | claimed |
| CN-117157291-A | Heterocyclic derivatives as P2X7 receptor antagonists | 布雷耶疗法有限公司 | 2023-12-01 | — | — | CN | claimed |
| EP-4262975-A1 | HETEROCYCLIC DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | Breye Therapeutics ApS (DK) | 2023-10-25 | — | — | EP | claimed |
| US-20230278996-A1 | YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | MOLECURE S.A. (PL) | 2023-09-07 | — | — | US | claimed |
| WO-2022129365-A1 | HETEROCYCLIC DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | AXXAM S.P.A. (IT) | 2022-06-23 | — | — | WO | claimed |
| EP-4015039-A1 | HETEROCYCLIC DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | AXXAM S.p.A. (IT) | 2022-06-22 | — | — | EP | claimed |
| EP-2375898-B1 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-16 | — | — | EP | claimed |
| WO-2024105104-A1 | MICROBIOCIDAL TETRAHYDROISOQUINOLINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-05-23 | — | — | WO | disclosed |
| US-20240034737-A1 | Heterocyclic Derivatives as P2X7 Receptor Antagonists | BREYE THERAPEUTICS APS (DK) | 2024-02-01 | — | — | US | disclosed |
| CN-117157291-A | Heterocyclic derivatives as P2X7 receptor antagonists | 布雷耶疗法有限公司 | 2023-12-01 | — | — | CN | disclosed |
| EP-4262975-A1 | HETEROCYCLIC DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | Breye Therapeutics ApS (DK) | 2023-10-25 | — | — | EP | disclosed |
| US-20230278996-A1 | YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | MOLECURE S.A. (PL) | 2023-09-07 | — | — | US | disclosed |
| WO-2022129365-A1 | HETEROCYCLIC DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | AXXAM S.P.A. (IT) | 2022-06-23 | — | — | WO | disclosed |
| EP-0773264-A1 | Process for the preparation of triphenodioxazine dyes amidated on both sides and triphenodioxazine dyes | DyStar Textilfarben GmbH & Co. Deutschland KG (DE) | 1997-05-14 | — | — | EP | disclosed |
| US-5625042-A | DYEING OR PRINTING MATERIAL HYDROXY OR AMIDE GROUPS BY APPLYING DYES WITH DISAZO AND TRIAZINE GROUPS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-29 | — | — | US | disclosed |
| EP-0769533-A1 | Disazoreactive dyes | BAYER AG (DE) | 1997-04-23 | — | — | EP | disclosed |
| US-5602076-A | INSECTICIDES, NEMATOCIDES | ZENECA LIMITED (GB) | 1997-02-11 | — | — | US | disclosed |
| EP-0685532-A1 | Novel reactive dyestuffs, their preparation and use | BAYER AG (DE) | 1995-12-06 | — | — | EP | disclosed |
| US-5470819-A | Plant growth regulators, insecticides | ZENECA LIMITED (GB) | 1995-11-28 | — | — | US | disclosed |
| US-5057146-A | CERTAIN 2-PYRIDYL OXY-PHENYL ACRYLATES HAVING FUNGICIDAL, INSECTICIDAL, NEMATOCIDAL AND PLANT GROWTH REGULATING ACTIVITY | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-15 | — | — | US | disclosed |