SCHEMBL4468948

SCHEMBL4468948

CCCCC(N=C=O)(N=C=O)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.32
MAPT P10636 1/20 0.32
AKR1B1 P15121 1/20 0.32
FDPS P14324 1/20 0.31
GPR84 Q9NQS5 7/20 0.31
PPARG P37231 6/20 0.31
PPARD Q03181 6/20 0.31
PPARA Q07869 6/20 0.31
HDAC11 Q96DB2 5/20 0.31
TSHR P16473 4/20 0.31
ALDH1A1 P00352 2/20 0.31
TLR2 O60603 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
FABP4 P15090 2/20 0.31
PTPN1 P18031 2/20 0.31
SLC22A6 Q4U2R8 1/20 0.31
SLC22A8 Q8TCC7 1/20 0.31
MEN1 O00255 1/20 0.31
ESR1 P03372 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10978133 0.92 CES2 (0.39) KMT2AMAPTGPR84PPARGPPARD
SCHEMBL10336346 0.88 ALDH1A1 (0.31) ALDH1A1
SCHEMBL7743766 0.81 KMT2A (0.33) KMT2AMAPTALDH1A1TDP1MEN1
SCHEMBL28799371 0.78 ALDH1A1 (0.32) KMT2AMAPTAKR1B1FDPSGPR84
SCHEMBL4907468 0.78 ALDH1A1 (0.32) KMT2AMAPTAKR1B1FDPSGPR84
SCHEMBL10629445 0.78 MEN1 (0.41) KMT2AMAPTPPARGPPARATSHR
SCHEMBL27782639 0.77 MAPT (0.31) KMT2AMAPTAKR1B1
SCHEMBL27413647 0.72 FDPS (0.31) FDPSALDH1A1
SCHEMBL5478038 0.72 FDPS (0.32) FDPS
SCHEMBL11402355 0.71 NAAA (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110511350-B Polycarbon type waterborne polyurethane and preparation method thereof 华南理工大学 2021-10-26 CN claimed
US-11008468-B2 Temporary decorative automotive/protective paint based on polyurethane dispersions COVESTRO LLC (US) 2021-05-18 US claimed
US-7098282-B2 Fluorosulfone-silicone hydrogel, RGP contact lenses, optical medical devices and compositions thereof NOVICKY NICK 2006-08-29 US claimed
US-20050176907-A1 Fluorosulfone-silicone hydrogel, RGP contact lenses, optical medical devices and compositions thereof NOVICKY NICK (CA) 2005-08-11 US claimed
EP-1455201-A1 Fluorosulfone-silicone hydrogel RGP contact lenses, optical medical devices and compositions thereof Novicky, Nick N. (CA) 2004-09-08 EP claimed
CN-110511350-B Polycarbon type waterborne polyurethane and preparation method thereof 华南理工大学 2021-10-26 CN disclosed
WO-2021085215-A1 POLYCARBODIIMIDE COMPOUND, AQUEOUS RESIN COMPOSITION AND FOOD PACKAGING CONTAINER 日清紡ケミカル株式会社 2021-05-06 WO disclosed
EP-3728371-A1 ADHESIVE BASED ON A SPECIAL POLYURETHANE UREA AND HAVING AN ADJUSTABLE ADHESIVE STRENGTH, PRODUCTION AND USE THEREOF Covestro Deutschland AG (DE) 2020-10-28 EP disclosed
EP-3679013-A1 METHOD FOR PRODUCING ISOCYANATES Covestro Deutschland AG (DE) 2020-07-15 EP disclosed
CN-110951294-A Active energy ray-curable resin composition, cured product, and laminate 荒川化学工业株式会社 2020-04-03 CN disclosed
WO-2019216700-A1 SOLID DISPERSION, PREPARATION METHOD THEREFOR, CHAIN-EXTENDED POLYURETHANE USING SAME, AND EPOXY RESIN COMPOSITION COMPRISING SAME 주식회사 삼양사 (KR) 2019-11-14 WO disclosed
EP-3347052-A1 POLYMER CONJUGATE COMPRISING A BIOACTIVE AGENT Polyactiva Pty Ltd (AU) 2018-07-18 EP disclosed
US-7098282-B2 Fluorosulfone-silicone hydrogel, RGP contact lenses, optical medical devices and compositions thereof NOVICKY NICK 2006-08-29 US disclosed
US-20050176907-A1 Fluorosulfone-silicone hydrogel, RGP contact lenses, optical medical devices and compositions thereof NOVICKY NICK (CA) 2005-08-11 US disclosed
EP-1455201-A1 Fluorosulfone-silicone hydrogel RGP contact lenses, optical medical devices and compositions thereof Novicky, Nick N. (CA) 2004-09-08 EP disclosed
WO-1999016619-A1 IMINE-CONTAINING CURATIVE FOR TWO COMPONENT POLYURETHANE STRUCTURAL ADHESIVES ASHLAND INC. (US) 1999-04-08 WO disclosed
US-4758625-A Acrylic crosslinked polymers ALBRIGHT & WILSON (AUSTRALIA) LIMITED (AU) 1988-07-19 US disclosed
EP-0214161-A4 ACRYLIC CROSSLINKED POLYMERS. ALBRIGHT & WILSON AUSTRALIA (AU) 1987-06-29 EP disclosed
EP-0214161-A1 ACRYLIC CROSSLINKED POLYMERS ALBRIGHT & WILSON (AUSTRALIA) LIMITED (AU) 1987-03-18 EP disclosed
WO-1986004591-A1 ACRYLIC CROSSLINKED POLYMERS ALBRIGHT & WILSON (AUSTRALIA) LIMITED (AU) 1986-08-14 WO disclosed