Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4467972 | 0.83 | VHL (0.35) | — | |
| SCHEMBL4461033 | 0.80 | EPHX2 (0.34) | EPHX2 | |
| SCHEMBL4460700 | 0.72 | IGF1R (0.36) | — | |
| SCHEMBL9285410 | 0.66 | — | — | |
| SCHEMBL443027 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL4302835 | 0.64 | NOTUM (0.43) | EPHX2 | |
| SCHEMBL4466158 | 0.63 | VHL (0.34) | — | |
| SCHEMBL4456076 | 0.62 | ALDH1A1 (0.38) | — | |
| SCHEMBL9629469 | 0.62 | — | — | |
| SCHEMBL2038427 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009017838-A2 | COMBINATIONS OF JAK-2 INHIBITORS AND OTHER AGENTS | EXELIXIS, INC. (US) | 2009-02-05 | — | — | WO | claimed |
| WO-2009017838-A2 | COMBINATIONS OF JAK-2 INHIBITORS AND OTHER AGENTS | EXELIXIS, INC. (US) | 2009-02-05 | — | — | WO | disclosed |