Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 7/20 | 0.39 |
| ▸ | CES2 | O00748 | 6/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 4/20 | 0.31 |
| ▸ | PPARD | Q03181 | 4/20 | 0.31 |
| ▸ | PPARA | Q07869 | 4/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.31 |
| ▸ | TLR2 | O60603 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6443118 | 0.82 | OR51E2 (0.37) | OR51E2 | |
| SCHEMBL4470308 | 0.77 | CES1 (0.33) | CES1CES2ALDH1A1AKR1B1TP53 | |
| SCHEMBL162501 | 0.74 | FNTA (0.46) | CES1CES2CA1ALDH1A1AKR1B1 | |
| SCHEMBL18606215 | 0.73 | THRB (0.40) | CES1CES2CA1ALDH1A1AKR1B1 | |
| SCHEMBL6440025 | 0.72 | CES1 (0.39) | CES1CES2CA1HAO1ALDH1A1 | |
| SCHEMBL1274509 | 0.70 | CES1 (0.36) | CES1CES2CA1HAO1ALDH1A1 | |
| SCHEMBL1074445 | 0.69 | FNTA (0.53) | CES1CES2ALDH1A1AKR1B1OR51E2 | |
| SCHEMBL18606216 | 0.69 | FNTA (0.44) | CES1CES2CA1ALDH1A1AKR1B1 | |
| SCHEMBL1074447 | 0.69 | FNTA (0.53) | CES1CES2ALDH1A1AKR1B1OR51E2 | |
| SCHEMBL21525695 | 0.69 | ALDH1A1 (0.38) | CES1CES2ALDH1A1AKR1B1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317294-B1 | ABSORBABLE ADHESIVE COMPOSITIONS | CLOSURE MEDICAL CORP (US) | 2005-03-16 | — | — | EP | claimed |