SCHEMBL4470560

SCHEMBL4470560

Cc1ccc([O])c(-c2ccccc2C(C)C)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.48
TRPA1 O75762 1/20 0.40
LMNA P02545 1/20 0.40
CHRM1 P11229 1/20 0.40
SLC6A2 P23975 1/20 0.40
ADRA1A P35348 1/20 0.40
HTR2B P41595 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
DHFR P00374 1/20 0.38
LPAR1 Q92633 3/20 0.38
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
CYP2A6 P11509 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
NPC1 O15118 1/20 0.36
KCNK3 O14649 1/20 0.35
KCNK9 Q9NPC2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL619072 0.79 LMNA (0.53) ELANETRPA1LMNACHRM1SLC6A2
SCHEMBL3684203 0.76 LPAR1 (0.48) ELANELMNALPAR1TDP1KCNK3
SCHEMBL167078 0.76 GABRA1 (0.55) TRPA1LMNASLC6A2HTR2BCA12
SCHEMBL29414063 0.76 GABRA1 (0.55) TRPA1LMNASLC6A2HTR2BCA12
SCHEMBL3773923 0.74 TRPA1 (0.50) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL3683159 0.74 GABRA1 (0.48) ELANETRPA1LMNACHRM1SLC6A2
SCHEMBL6668337 0.74 TRPA1 (0.60) ELANETRPA1LMNACHRM1SLC6A2
SCHEMBL30320821 0.74 TRPA1 (0.60) ELANETRPA1LMNACHRM1SLC6A2
SCHEMBL9174922 0.73 GABRA1 (0.52) TRPA1LMNASLC6A2HTR2BCA12
SCHEMBL14122570 0.72 ELANE (0.39) ELANETRPA1LMNACHRM1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2010576-B1 BIS-ARYLARYLOXY CATALYTIC SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMERS OR ETHYLENE COPOLYMERS WITH ALPHA-OLEFINS SK INNOVATION CO LTD (KR) 2013-07-24 EP disclosed
EP-2010576-A1 BIS-ARYLARYLOXY CATALYTIC SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMERS OR ETHYLENE COPOLYMERS WITH ALPHA-OLEFINS SK Energy Co., Ltd. (KR) 2009-01-07 EP disclosed
WO-2007123362-A1 BIS-ARYLARYLOXY CATALYTIC SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMERS OR ETHYLENE COPOLYMERS WITH ALPHA-OLEFINS SK ENERGY CO., LTD. (KR) 2007-11-01 WO disclosed