SCHEMBL3683159

SCHEMBL3683159

Cc1cc(-c2ccccc2C(C)C)c(O)c(-c2ccccc2C(C)C)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 6/20 0.48
GABRB1 P18505 5/20 0.48
GABRB2 P47870 3/20 0.48
CA1 P00915 3/20 0.48
CA2 P00918 3/20 0.48
LMNA P02545 2/20 0.48
SLC6A2 P23975 2/20 0.48
HTR2B P41595 2/20 0.48
FAAH O00519 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
HPGD P15428 1/20 0.48
TSHR P16473 1/20 0.48
GABRG2 P18507 1/20 0.48
PTGS1 P23219 1/20 0.48
HTR2C P28335 1/20 0.48
GABRB3 P28472 1/20 0.48
GABRA5 P31644 1/20 0.48
GABRA3 P34903 1/20 0.48
GABRA2 P47869 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22320325 0.86 GABRA1 (0.41) GABRA1GABRB1GABRB2CA1CA2
SCHEMBL23198665 0.84 GABRA1 (0.62) GABRA1GABRB1GABRB2CA1CA2
SCHEMBL30336636 0.84 GABRA1 (0.62) GABRA1GABRB1GABRB2CA1CA2
SCHEMBL23198660 0.83 GABRA1 (0.53) GABRA1GABRB1GABRB2CA1CA2
SCHEMBL619072 0.81 LMNA (0.53) GABRA1GABRB1GABRB2CA1CA2
SCHEMBL22356534 0.80 TRPA1 (0.36) GABRA1GABRB1GABRB2CA1CA2
Hydrogen Peroxide SCHEMBL9644435 0.79 GABRA1 (0.56) GABRA1GABRB1GABRB2CA1CA2
SCHEMBL167078 0.78 GABRA1 (0.55) GABRA1GABRB1GABRB2CA1CA2
SCHEMBL29414063 0.78 GABRA1 (0.55) GABRA1GABRB1GABRB2CA1CA2
SCHEMBL3685655 0.78 CDC25A (0.40) GABRA1GABRB2CA1CA2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1910427-B1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFINS SK INNOVATION CO LTD (KR) 2015-05-13 EP disclosed
US-7833926-B2 Arylphenoxy catalyst system for producing ethylene homopolymer or copolymers of ethylene and α-olefins SK ENERGY CO., LTD. (KR) 2010-11-16 US disclosed
US-20090326175-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND a-OLEFINS SK ENERGY CO., LTD. (KR) 2009-12-31 US disclosed
US-7589042-B2 Arylphenoxy catalyst system for producing ethylene homopolymer or copolymers of ethylene and α-olefins SK CORPORATION (KR) 2009-09-15 US disclosed
EP-1910427-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFINS SK Energy Co., Ltd. (KR) 2008-04-16 EP disclosed
US-20070135297-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND a-OLEFINS SK CORPORATION (KR) 2007-06-14 US disclosed
WO-2007040294-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFINS SK ENERGY CO., LTD. (KR) 2007-04-12 WO disclosed
US-20070004586-A1 Arylphenoxy catalyst system for producing ethylene homopolymer or copolymers of ethylene and alpha-olefins SK CORPORATION (KR) 2007-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090326175-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND a-OLEFINS ESR1, ERO1A, PPOX GABRA1 2919/4885GABRB1 2435/4885GABRB2 2439/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.