Dimethylamine

Dimethylamine

SCHEMBL447225

CCC=C(C)C(=O)OCC.CNC

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLO1 Q04760 1/20 0.45
CYP2D6 P10635 2/20 0.43
CYP2C19 P33261 1/20 0.43
MAPT P10636 2/20 0.41
ALDH1A1 P00352 5/20 0.41
LMNA P02545 2/20 0.41
HSD17B10 Q99714 1/20 0.41
NPSR1 Q6W5P4 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
EGLN1 Q9GZT9 1/20 0.38
TRPA1 O75762 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
S1PR4 O95977 1/20 0.36
S1PR1 P21453 1/20 0.36
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1618911 0.94 GLO1 (0.50) GLO1CYP2D6CYP2C19MAPTALDH1A1
SCHEMBL134789 0.94 GLO1 (0.50) GLO1CYP2D6CYP2C19MAPTALDH1A1
Water SCHEMBL7175634 0.91 GLO1 (0.48) GLO1CYP2D6CYP2C19MAPTALDH1A1
Ethylamine SCHEMBL28000277 0.88 GLO1 (0.45) GLO1CYP2D6CYP2C19MAPTALDH1A1
Trimethylammonium SCHEMBL17712424 0.88 GLO1 (0.45) GLO1CYP2D6CYP2C19MAPTALDH1A1
Trimethylammonium SCHEMBL16429829 0.88 GLO1 (0.45) GLO1CYP2D6CYP2C19MAPTALDH1A1
Acrylic Acid SCHEMBL28082177 0.84 CYP2D6 (0.44) GLO1CYP2D6CYP2C19MAPTALDH1A1
Dimethylamine SCHEMBL27509730 0.83 GLO1 (0.48) GLO1CYP2D6CYP2C19MAPTALDH1A1
Sulfuric Acid SCHEMBL3054230 0.81 GLO1 (0.40) GLO1CYP2D6CYP2C19MAPTALDH1A1
SCHEMBL12984317 0.80 THRB (0.42) GLO1CYP2D6CYP2C19ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160199282-A1 PERFORMANCE-ENHANCED HAIR TREATMENT COMPOSITION HENKEL AG & CO. KGAA (DE) 2016-07-14 US disclosed
US-20120060856-A1 Cosmetic Composition and Reshaping Method for Keratinic Fibers HENKEL AG & CO. KGAA (DE) 2012-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120060856-A1 Cosmetic Composition and Reshaping Method for Keratinic Fibers H1-0, H1-3, H1-2 GLO1 2272/4885CYP2D6 2121/4885CYP2C19 3063/4885
US-20160199282-A1 PERFORMANCE-ENHANCED HAIR TREATMENT COMPOSITION KRT18, YWHAZ, PHYKPL GLO1 314/4885CYP2D6 3416/4885CYP2C19 3283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.