Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 4/20 | 0.58 |
| ▸ | FLT1 | P17948 | 5/20 | 0.48 |
| ▸ | FLT4 | P35916 | 5/20 | 0.48 |
| ▸ | KDR | P35968 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 2/20 | 0.43 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CCKBR | P32239 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4196234 | 0.80 | KDM4E (0.68) | FLT1FLT4KDRKDM4EHPGD | |
| SCHEMBL4477897 | 0.80 | FLT1 (0.67) | KAT6AFLT1FLT4KDRKDM4E | |
| SCHEMBL6850238 | 0.77 | KAT6A (0.51) | KAT6AKDM4EPGRACLYPTGES2 | |
| SCHEMBL17127741 | 0.76 | KAT6A (0.53) | KAT6APGRACLYRXFP1CCKBR | |
| SCHEMBL5666232 | 0.76 | HTT (0.72) | HTTRXFP1 | |
| SCHEMBL5958934 | 0.76 | FLT1 (0.65) | KAT6AFLT1FLT4KDRRXFP1 | |
| SCHEMBL4476657 | 0.75 | HPGD (0.55) | KAT6AFLT1FLT4KDRKDM4E | |
| SCHEMBL4472286 | 0.74 | CYP2C9 (0.58) | KAT6APGRHTTACLY | |
| SCHEMBL19006934 | 0.73 | KAT6A (0.50) | KAT6APGRACLYPTGES2RXFP1 | |
| SCHEMBL420253 | 0.73 | PGR (0.54) | KAT6APGRACLYPTGES2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009067607-A2 | COMBINATIONS OF PDE4 INHIBITORS AND ANTIPSYCHOTICS FOR THE TREATMENT OF PSYCHOTIC DISORDERS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2009-05-28 | — | — | WO | disclosed |