Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | FBP1 | P09467 | 1/20 | 0.51 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.51 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.51 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | ACP1 | P24666 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ACLY | P53396 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6295746 | 0.83 | CA12 (0.69) | CYP2C9MAPTMEN1KMT2ALMNA | |
| SCHEMBL4196236 | 0.81 | LMNA (0.78) | CYP2C9MAPTLMNAFBP1CA12 | |
| SCHEMBL19334523 | 0.80 | PGR (0.77) | ALDH1A1MEN1KMT2APGRACLY | |
| SCHEMBL4477902 | 0.79 | FBP1 (0.79) | MAPTMEN1KMT2ALMNAPGR | |
| SCHEMBL17127741 | 0.79 | KAT6A (0.53) | MAPTPGRKAT6AACLY | |
| SCHEMBL6301527 | 0.78 | MAPT (0.58) | CYP2C9MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7803480 | 0.78 | NR1H3 (0.62) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6850238 | 0.76 | KAT6A (0.51) | PGRKAT6ACA1CA2ACLY | |
| SCHEMBL19006934 | 0.75 | KAT6A (0.50) | MAPTPGRKAT6AACLY | |
| SCHEMBL16396241 | 0.75 | SMN1; SMN2 (0.51) | MAPTALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009067607-A2 | COMBINATIONS OF PDE4 INHIBITORS AND ANTIPSYCHOTICS FOR THE TREATMENT OF PSYCHOTIC DISORDERS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2009-05-28 | — | — | WO | disclosed |