Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | FLT1 | P17948 | 8/20 | 0.53 |
| ▸ | FLT4 | P35916 | 8/20 | 0.53 |
| ▸ | KDR | P35968 | 8/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | FADS1 | O60427 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | KAT7 | O95251 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4457676 | 0.84 | EGFR (0.59) | HPGDFLT1FLT4KDRPOLB | |
| SCHEMBL4477897 | 0.81 | FLT1 (0.67) | FLT1FLT4KDRKDM4EKAT6A | |
| SCHEMBL4196234 | 0.81 | KDM4E (0.68) | HPGDFLT1FLT4KDRPOLB | |
| SCHEMBL4472196 | 0.77 | HPGD (0.47) | HPGDFLT1FLT4KDRPOLB | |
| SCHEMBL4472284 | 0.75 | KAT6A (0.58) | HPGDFLT1FLT4KDRKDM4E | |
| SCHEMBL23918989 | 0.74 | CA9 (0.47) | HPGDFLT1FLT4KDRFADS1 | |
| SCHEMBL4477501 | 0.73 | KDM4E (0.47) | HPGDFLT1FLT4KDRPOLB | |
| SCHEMBL5958991 | 0.73 | FLT1 (0.78) | FLT1FLT4KDR | |
| SCHEMBL19634273 | 0.72 | KMT2A (0.52) | FLT1FLT4KDRMEN1LMNA | |
| SCHEMBL7716801 | 0.72 | PKM (0.60) | FLT1FLT4KDRPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009067607-A2 | COMBINATIONS OF PDE4 INHIBITORS AND ANTIPSYCHOTICS FOR THE TREATMENT OF PSYCHOTIC DISORDERS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2009-05-28 | — | — | WO | disclosed |