SCHEMBL44730

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24631978	0.82	CYP19A1 (0.53)	HDAC6CYP1A2CYP2C19SMN1; SMN2CYP19A1
	SCHEMBL14853003	0.82	PRMT5 (0.39)	HDAC6BCHEACHESMPD1PARP1
	SCHEMBL19768708	0.77	AHR (0.59)	AHRKDM4EMAPTMEN1ALDH1A1
	SCHEMBL14839698	0.77	HDAC6 (0.50)	HDAC6BCHEACHESMPD1CYP1A2
	SCHEMBL11209828	0.74	BCHE (0.67)	HDAC6BCHEACHESMPD1CYP1A2
	SCHEMBL29643279	0.74	BCHE (0.67)	HDAC6BCHEACHESMPD1CYP1A2
	SCHEMBL14839671	0.73	PTGER4 (0.47)	HDAC6BCHEACHESMPD1KDM4E
	SCHEMBL869229	0.72	AHR (0.53)	CYP1A2CYP2C19SMN1; SMN2AHRKDM4E
	SCHEMBL2311195	0.72	AHR (0.53)	RAB9ASMN1; SMN2AHRKDM4EMAPT
	SCHEMBL12997524	0.72	KIF11 (0.59)	RAB9ASMN1; SMN2AHRKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.