Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8817458 | 0.85 | KDM4E (0.37) | KDM4EPKM | |
| SCHEMBL6267812 | 0.78 | SIGMAR1 (0.32) | KDM4EPKMSIGMAR1 | |
| SCHEMBL10908284 | 0.76 | KDM4E (0.34) | KDM4EPKMSIGMAR1 | |
| SCHEMBL7064134 | 0.76 | KDM4E (0.34) | KDM4EPKM | |
| SCHEMBL5701610 | 0.75 | KDM4E (0.36) | KDM4EPKM | |
| SCHEMBL556904 | 0.75 | KDM4E (0.36) | KDM4EPKM | |
| Acetic Acid SCHEMBL28569985 | 0.73 | ALDH1A1 (0.38) | KDM4EPKM | |
| SCHEMBL31186268 | 0.72 | KDM4E (0.34) | KDM4EPKM | |
| SCHEMBL2800949 | 0.72 | KDM4E (0.34) | KDM4EPKM | |
| SCHEMBL5159548 | 0.72 | KDM4E (0.34) | KDM4EPKMSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582660-B2 | 2-thio-substituted imidazole derivatives and their use in pharmaceutics | C-A-I-R BIOSCIENCES GMBH (DE) | 2009-09-01 | — | — | US | disclosed |
| US-20060235054-A1 | 2-Thio-substituted imidazole derivatives and their use in pharmaceutics | MERCKLE-GMBH (DE) | 2006-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060235054-A1 | 2-Thio-substituted imidazole derivatives and their use in pharmaceutics | IL2, TPMT, IFNG | KDM4E 3785/4885PKM 1486/4885SIGMAR1 333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.