SCHEMBL4473565

SCHEMBL4473565

CCS(=O)(=O)c1nc2ccccn2c1S(=O)(=O)NC(=O)Nc1ncc(OC)c(OC)n1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.35
LMNA P02545 2/20 0.35
TP53 P04637 1/20 0.35
ALDH1A1 P00352 3/20 0.34
KDM4E B2RXH2 2/20 0.34
HSD17B10 Q99714 2/20 0.34
DAPK3 O43293 1/20 0.34
JAK2 O60674 1/20 0.34
PRKD3 O94806 1/20 0.34
MAP4K4 O95819 1/20 0.34
ABL1 P00519 1/20 0.34
CSF1R P07333 1/20 0.34
RET P07949 1/20 0.34
MET P08581 1/20 0.34
PDGFRA P16234 1/20 0.34
PRKACA P17612 1/20 0.34
LTK P29376 1/20 0.34
GRK5 P34947 1/20 0.34
KDR P35968 1/20 0.34
MAPK8 P45983 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6832941 0.86 RAB9A (0.41) MAPTLMNATP53ALDH1A1KDM4E
SCHEMBL8461112 0.84 CDK2 (0.40) MAPTTP53ALDH1A1KDM4EHSD17B10
Sulfosulfuron SCHEMBL66574 0.83 GAA (0.49) MAPTTP53ALDH1A1KDM4EHSD17B10
Sulfosulfuron SCHEMBL8476425 0.80 GAA (0.46) MAPTTP53ALDH1A1KDM4EHSD17B10
SCHEMBL7189218 0.76 FBP1 (0.39) MAPTLMNATP53ALDH1A1KDM4E
SCHEMBL8478141 0.73 GAA (0.49) MAPTTP53ALDH1A1KDM4ENPC1
SCHEMBL10968069 0.73 CA2 (0.43) MAPTALDH1A1KDM4EKMT2ANPC1
SCHEMBL8480505 0.73 GAA (0.53) MAPTTP53ALDH1A1KDM4EHSD17B10
SCHEMBL11269372 0.73 KDM4E (0.41) MAPTLMNAALDH1A1KDM4EKMT2A
Sulfosulfuron SCHEMBL14655298 0.72 GAA (0.38) MAPTTP53ALDH1A1KDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009064001-A2 HERBICIDAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-05-22 WO claimed
WO-2007132703-A1 HERBICIDAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-11-22 WO claimed
WO-2007132703-A1 HERBICIDAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-11-22 WO disclosed
EP-1791425-A2 SAFENING METHOD Bayer CropScience AG (DE) 2007-06-06 EP disclosed
WO-2006007982-A2 SAFENING METHOD BAYER CROPSCIENCE GMBH (DE) 2006-01-26 WO disclosed