SCHEMBL7189218

SCHEMBL7189218

CCS(=O)(=O)c1nc2ccccn2c1S(=O)(=O)NC(=O)Nc1cc(OC)cc(OC)n1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 2/20 0.39
CREBBP Q92793 1/20 0.39
MAPT P10636 4/20 0.36
TP53 P04637 2/20 0.36
GLA P06280 1/20 0.36
RAB9A P51151 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MAPK1 P28482 1/20 0.36
LMNA P02545 2/20 0.36
GAA P10253 1/20 0.36
ALDH1A1 P00352 2/20 0.35
KDM4E B2RXH2 1/20 0.35
PKM P14618 1/20 0.35
HTT P42858 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfosulfuron SCHEMBL66574 0.87 GAA (0.49) MAPTTP53GLARAB9ASMN1; SMN2
SCHEMBL5904842 0.86 RAB9A (0.46) FBP1CREBBPMAPTTP53RAB9A
Sulfosulfuron SCHEMBL8476425 0.84 GAA (0.46) MAPTTP53GLARAB9ASMN1; SMN2
SCHEMBL8461112 0.81 CDK2 (0.40) MAPTTP53GLARAB9AGAA
SCHEMBL4473565 0.76 MAPT (0.35) MAPTTP53RAB9ALMNAGAA
Sulfosulfuron SCHEMBL14655515 0.76 GAA (0.39) MAPTTP53GLARAB9ASMN1; SMN2
Sulfosulfuron SCHEMBL6429101 0.75 GAA (0.40) MAPTTP53GLASMN1; SMN2GAA
SCHEMBL2954512 0.75 FBP1 (0.40) FBP1CREBBPMAPTTP53GLA
Sulfosulfuron SCHEMBL14655298 0.74 GAA (0.38) MAPTTP53GLASMN1; SMN2GAA
SCHEMBL8478141 0.74 GAA (0.49) MAPTTP53GLASMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030176284-A1 Herbicide combination with acylated aminophenylsulfonylureas BAYER CROPSCIENCE GMBH (DE) 2003-09-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030176284-A1 Herbicide combination with acylated aminophenylsulfonylureas AADAC, DDT, DDC FBP1 1044/4885CREBBP 4435/4885MAPT 4481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.