Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 3/20 | 0.47 |
| ▸ | GRN | P28799 | 1/20 | 0.47 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SDHB | P21912 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12632739 | 0.85 | MYC (0.52) | MAPTTHRBMYCSMN1; SMN2SDHB | |
| SCHEMBL5097191 | 0.85 | KLKB1 (0.45) | KLKB1MAPTSMN1; SMN2POLBAPEX1 | |
| SCHEMBL12572951 | 0.84 | MAPT (0.43) | MAPTTHRBMYCSMN1; SMN2SDHB | |
| SCHEMBL2254831 | 0.79 | RXRA (0.48) | KDM4EALDH1A1F10 | |
| SCHEMBL950585 | 0.78 | KLKB1 (0.52) | KLKB1GRNSORT1MAPTKDM4E | |
| SCHEMBL1670472 | 0.78 | GRN (0.56) | KLKB1GRNSORT1MAPTTHRB | |
| SCHEMBL7230395 | 0.78 | KDM4E (0.48) | MAPTTHRBSMN1; SMN2TP53POLB | |
| SCHEMBL4477762 | 0.77 | CARM1 (0.42) | KLKB1TP53CARM1F10 | |
| SCHEMBL3471251 | 0.77 | KLKB1 (0.46) | KLKB1GRNSORT1MAPTTHRB | |
| SCHEMBL7229018 | 0.76 | F10 (0.45) | KLKB1GRNSORT1CARM1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541377-B2 | Substituted anthranilamides for controlling invertebrate pests | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-06-02 | — | — | US | disclosed |
| CN-100453532-C | Substituted anthranilamides for controlling invertebrate pests | DU PONT (US) | 2009-01-21 | — | — | CN | disclosed |
| EP-1417176-B1 | SUBSTITUTED ANTHRANILAMIDES FOR CONTROLLING INVERTEBRATE PESTS | DU PONT (US) | 2008-12-17 | — | — | EP | disclosed |
| US-20070203201-A1 | Substituted anthranilamides for controlling invertebrate pests | FINKELSTEIN BRUCE L | 2007-08-30 | — | — | US | disclosed |
| US-7199138-B2 | Substituted anthranilamides for controlling invertebrate pests | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-04-03 | — | — | US | disclosed |
| US-20050282868-A1 | Substituted anthranilamides for controlling invertebrate pests | E. I. DU PONT DE NEMOURS AND COMPANY | 2005-12-22 | — | — | US | disclosed |
| CN-1653051-A | Substituted anthranilamides for controlling invertebrate pests | DU PONT (US) | 2005-08-10 | — | — | CN | disclosed |
| EP-1417176-A1 | SUBSTITUTED ANTHRANILAMIDES FOR CONTROLLING INVERTEBRATE PESTS | E. I. du Pont de Nemours and Company (US) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003016284-A1 | SUBSTITUTED ANTHRANILAMIDES FOR CONTROLLING INVERTEBRATE PESTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-02-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203201-A1 | Substituted anthranilamides for controlling invertebrate pests | ANTXR2, PRXL2A, F9 | KLKB1 4573/4885GRN 3233/4885SORT1 4580/4885 |
| US-20050282868-A1 | Substituted anthranilamides for controlling invertebrate pests | ANTXR2, PRXL2A, F9 | KLKB1 4524/4885GRN 3121/4885SORT1 4575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.