Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4478245 | 0.82 | HRH3 (0.48) | HRH3 | |
| SCHEMBL4479047 | 0.74 | HRH3 (0.46) | HRH3 | |
| SCHEMBL3776595 | 0.73 | HRH3 (0.62) | HRH3 | |
| SCHEMBL4485943 | 0.73 | HRH3 (0.45) | HRH3 | |
| SCHEMBL3776585 | 0.72 | HRH3 (0.52) | HRH3 | |
| SCHEMBL4564958 | 0.68 | HRH1 (0.50) | HRH3 | |
| SCHEMBL4481591 | 0.67 | HRH1 (0.42) | — | |
| SCHEMBL11918729 | 0.66 | HRH3 (1.00) | HRH3 | |
| SCHEMBL3085867 | 0.65 | HRH3 (1.00) | HRH3 | |
| SCHEMBL11918570 | 0.65 | HRH3 (1.00) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009039431-A2 | SUBSTITUTED ARYL-FUSED SPIROCYCLIC AMINES | NEUROGEN CORPORATION (US) | 2009-03-26 | — | — | WO | claimed |