Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.30 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.30 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4474871 | 1.00 | GNAI3 (0.30) | GNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL4476787 | 0.98 | GNAI3 (0.33) | GNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL4476786 | 0.98 | GNAI3 (0.33) | GNAI3GNAO1GNAI1 | |
| SCHEMBL13116715 | 0.87 | — | — | |
| SCHEMBL28210693 | 0.78 | — | — | |
| SCHEMBL14077938 | 0.76 | CHRM2 (0.37) | — | |
| SCHEMBL28021279 | 0.73 | — | — | |
| SCHEMBL18427101 | 0.70 | — | — | |
| SCHEMBL19544089 | 0.70 | — | — | |
| SCHEMBL17645614 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524963-B2 | Synthesis of (4-bromophenyl)(4-piperidyl)methanone-(Z)-O-ethyloxime and salts | SCHERING CORPORATION (US) | 2009-04-28 | — | — | US | disclosed |
| US-7524963-B2 | Synthesis of (4-bromophenyl)(4-piperidyl)methanone-(Z)-O-ethyloxime and salts | SCHERING CORPORATION (US) | 2009-04-28 | — | — | US | disclosed |
| CN-1308308-C | Synthesis of (4-bromopnenyl)(4-piperidyl)methanone-(z)-o-ethyloxime and salts | SCHERING CORP (US) | 2007-04-04 | — | — | CN | disclosed |
| US-20050171159-A1 | Antiinflammatory agents; rheumatic diseases | WONG GEORGE S (US) | 2005-08-04 | — | — | US | disclosed |
| US-20050171159-A1 | Antiinflammatory agents; rheumatic diseases | WONG GEORGE S (US) | 2005-08-04 | — | — | US | disclosed |
| US-6914142-B2 | Synthesis of (4-bromopnenyl)(4-piperidyl)methanone-(Z)-O-ethyloxime and salts | SCHERING CORPORATION (US) | 2005-07-05 | — | — | US | disclosed |
| US-6914142-B2 | Synthesis of (4-bromopnenyl)(4-piperidyl)methanone-(Z)-O-ethyloxime and salts | SCHERING CORPORATION (US) | 2005-07-05 | — | — | US | disclosed |
| CN-1571768-A | Synthesis of (4-bromopnenyl)(4-piperidyl)methanone-(z)-o-ethyloxime and salts | SCHERING CORP (US) | 2005-01-26 | — | — | CN | disclosed |
| EP-1436262-A1 | SYNTHESIS OF (4-BROMOPHENYL) (4-PIPERIDYL)METHANONE-(Z)-O-ETHYLOXIME AND SALTS | Schering Corporation (US) | 2004-07-14 | — | — | EP | disclosed |
| US-20030092731-A1 | Synthesis of (4-bromopnenyl)(4-piperidyl)methanone-(Z)-O-ethyloxime and salts | SCHERING CORPORATION | 2003-05-15 | — | — | US | disclosed |
| US-20030092731-A1 | Synthesis of (4-bromopnenyl)(4-piperidyl)methanone-(Z)-O-ethyloxime and salts | SCHERING CORPORATION | 2003-05-15 | — | — | US | disclosed |
| WO-2003033465-A1 | SYNTHESIS OF (4-BROMOPHENYL) (4-PIPERIDYL)METHANONE-(Z)-O-ETHYLOXIME AND SALTS | SCHERING CORPORATION (US) | 2003-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092731-A1 | Synthesis of (4-bromopnenyl)(4-piperidyl)methanone-(Z)-O-ethyloxime and salts | PAM, PNMT, MSMO1 | GNAI3 1246/4885GNAO1 344/4885GNAI1 2272/4885 |
| US-20050171159-A1 | Antiinflammatory agents; rheumatic diseases | PTGES3, PTGES, PTGES2 | GNAI3 919/4885GNAO1 759/4885GNAI1 1253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.