Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | GNRHR | P30968 | 10/20 | 0.43 |
| ▸ | HTR6 | P50406 | 3/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13868913 | 0.88 | TP53 (0.42) | GNRHRNPC1RAB9AGFER | |
| SCHEMBL4465207 | 0.81 | HTR1A (0.46) | HTR1AHTR3AHTR2AGNRHRHTR6 | |
| SCHEMBL4462439 | 0.80 | LMNA (0.45) | GNRHR | |
| SCHEMBL4481231 | 0.76 | GNRHR (0.70) | GNRHR | |
| SCHEMBL3274724 | 0.75 | GNRHR (0.70) | GNRHR | |
| SCHEMBL4479487 | 0.75 | GNRHR (0.68) | GNRHR | |
| SCHEMBL4476578 | 0.74 | TNF (0.49) | HTR1AHTR3AHTR2AHTR2CSLC6A4 | |
| SCHEMBL14666780 | 0.74 | NPC1 (0.49) | NPC1RAB9AGFER | |
| SCHEMBL10236253 | 0.73 | NPC1 (0.55) | NPC1RAB9AGFER | |
| SCHEMBL4476570 | 0.72 | GNRHR (0.53) | HTR2AGNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531542-B2 | Benzooxazole and benzothiazole antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2009-05-12 | — | — | US | disclosed |
| US-7531542-B2 | Benzooxazole and benzothiazole antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2009-05-12 | — | — | US | disclosed |
| US-7531542-B2 | Benzooxazole and benzothiazole antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2009-05-12 | — | — | US | disclosed |
| US-20060264631-A1 | Benzooxazole and benzothiazole antagonists of gonadotropin releasing hormone receptor | WYETH (US) | 2006-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264631-A1 | Benzooxazole and benzothiazole antagonists of gonadotropin releasing hormone receptor | GNRHR, GHRHR, LHCGR | HTR1A 854/4885HTR3A 848/4885HTR2A 717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.