Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 13/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13006486 | 0.92 | LMNA (0.55) | LMNAPOLBCHRNA7DHODHEGFR | |
| SCHEMBL1145119 | 0.86 | LMNA (0.53) | LMNAPOLBDHODHEGFR | |
| SCHEMBL3385594 | 0.84 | CHRNA7 (0.41) | LMNAPOLBCHRNA7DHODHEGFR | |
| SCHEMBL2793907 | 0.84 | LMNA (0.53) | LMNAPOLBDHODHEGFR | |
| SCHEMBL1145148 | 0.83 | CHRNA7 (0.43) | CHRNA7DHODHEGFRCHRM3MAOA | |
| SCHEMBL1134823 | 0.83 | LMNA (0.53) | LMNAPOLBDHODH | |
| SCHEMBL21069191 | 0.83 | LMNA (0.64) | LMNAPOLBDHODHEGFR | |
| SCHEMBL29445397 | 0.83 | LMNA (0.53) | LMNAPOLBDHODH | |
| SCHEMBL4477674 | 0.81 | CHRNA7 (0.42) | CHRNA7DHODHEGFRCHRM3MAOA | |
| SCHEMBL4455883 | 0.80 | LMNA (0.45) | LMNAPOLBDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521397-B2 | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2009-04-21 | — | — | US | disclosed |
| US-7329633-B2 | Disubstituted pyrazolylcarboxanilides | BAYER CROPSCIENCE AG (DE) | 2008-02-12 | — | — | US | disclosed |
| US-20080015244-A1 | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2008-01-17 | — | — | US | disclosed |
| US-20060116414-A1 | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116414-A1 | Disubstituted pyrazolyl carboxanilides | MRPL21, RRS1, CBR3 | LMNA 4412/4885POLB 1290/4885CHRNA7 3475/4885 |
| US-20080015244-A1 | Disubstituted pyrazolyl carboxanilides | MRPL21, CBR3, CBR1 | LMNA 4600/4885POLB 1757/4885CHRNA7 3399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.