Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 17/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL973104 | 0.90 | LMNA (0.56) | LMNAPOLBATMDHODH | |
| SCHEMBL3387363 | 0.81 | ATM (0.47) | LMNAPOLBATMDHODH | |
| SCHEMBL973238 | 0.80 | ATM (0.47) | ATMDHODH | |
| SCHEMBL4477671 | 0.80 | LMNA (0.45) | LMNAPOLBDHODH | |
| SCHEMBL4455890 | 0.78 | ATM (0.46) | ATMDHODH | |
| SCHEMBL28354155 | 0.76 | LMNA (0.56) | LMNAPOLBDHODH | |
| SCHEMBL973770 | 0.76 | LMNA (0.62) | LMNAPOLBDHODH | |
| SCHEMBL2474435 | 0.76 | LMNA (0.46) | LMNAPOLBATMDHODH | |
| SCHEMBL28345856 | 0.72 | LMNA (0.51) | LMNAPOLBDHODH | |
| SCHEMBL973052 | 0.72 | ATM (0.69) | LMNAPOLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100503577-C | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2009-06-24 | — | — | CN | disclosed |
| US-7521397-B2 | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2009-04-21 | — | — | US | disclosed |
| US-7329633-B2 | Disubstituted pyrazolylcarboxanilides | BAYER CROPSCIENCE AG (DE) | 2008-02-12 | — | — | US | disclosed |
| US-20080015244-A1 | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2008-01-17 | — | — | US | disclosed |
| US-20060116414-A1 | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-06-01 | — | — | US | disclosed |
| CN-1646494-A | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2005-07-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116414-A1 | Disubstituted pyrazolyl carboxanilides | MRPL21, RRS1, CBR3 | LMNA 4412/4885POLB 1290/4885ATM 1894/4885 |
| US-20080015244-A1 | Disubstituted pyrazolyl carboxanilides | MRPL21, CBR3, CBR1 | LMNA 4600/4885POLB 1757/4885ATM 1622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.