SCHEMBL44791

SCHEMBL44791

C=CC(C(=O)c1ccccc1SC)N1CCOCC1

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.58
HTT P42858 4/20 0.44
KMT2A Q03164 5/20 0.40
TSHR P16473 3/20 0.40
POLB P06746 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
MAPT P10636 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C19 P33261 1/20 0.40
MEN1 O00255 3/20 0.39
RAB9A P51151 1/20 0.39
LMNA P02545 1/20 0.38
RECQL P46063 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thioxanthene SCHEMBL3387198 0.88 ALDH1A1 (0.46) ALDH1A1HTTKMT2ATSHRPOLB
SCHEMBL6148679 0.83 ALDH1A1 (0.62) ALDH1A1HTTKMT2ATSHRPOLB
SCHEMBL31467399 0.83 ALDH1A1 (0.62) ALDH1A1HTTKMT2ATSHRPOLB
SCHEMBL30484626 0.76 ALDH1A1 (0.52) ALDH1A1HTTKMT2ATSHRPOLB
SCHEMBL50851 0.74 ALDH1A1 (1.00) ALDH1A1HTTKMT2ATSHRSMN1; SMN2
SCHEMBL8901445 0.71 ALDH1A1 (0.53) ALDH1A1HTTKMT2ATSHRPOLB
SCHEMBL29686523 0.70 ALDH1A1 (0.63) ALDH1A1HTTKMT2ATSHRPOLB
SCHEMBL218736 0.70 ALDH1A1 (0.63) ALDH1A1HTTKMT2ATSHRPOLB
SCHEMBL44792 0.68 SMN1; SMN2 (0.48) ALDH1A1HTTTSHRPOLBSMN1; SMN2
SCHEMBL8214576 0.67 KMT2A (0.54) ALDH1A1HTTKMT2ATSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109071976-B Radiation curable ink formulations 富林特集团瑞典有限公司 2022-06-03 CN disclosed
US-10252291-B2 Photo-curing of thermoplastic coatings COLOPLAST A/S (DK) 2019-04-09 US disclosed
EP-2850112-B1 NOVEL POLYMERIC PHOTOINITIATORS AND PHOTOINITIATOR MONOMERS COLOPLAST AS (DK) 2018-11-21 EP disclosed
EP-2850111-B1 NOVEL POLYMERIC PHOTOINITIATORS AND PHOTOINITIATOR MONOMERS COLOPLAST AS (DK) 2018-11-21 EP disclosed
EP-3369751-A1 NOVEL PHOTOINITIATORS Coloplast A/S (DK) 2018-09-05 EP disclosed
US-10040902-B2 Polymeric photoinitiators COLOPLAST A/S (DK) 2018-08-07 US disclosed
EP-2394676-B1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITIATOR-CONTAINING SCAFFOLDS COLOPLAST AS (DK) 2018-03-28 EP disclosed
EP-2638076-B1 NOVEL PHOTOINITIATORS COLOPLAST AS (DK) 2018-03-28 EP disclosed
EP-2585494-B1 HYDROPHILIC GELS FROM POLYALKYLETHER-BASED PHOTOINITIATORS COLOPLAST AS (DK) 2017-08-09 EP disclosed
EP-2850113-B1 NOVEL POLYMERIC PHOTOINITIATORS AND PHOTOINITIATOR MONOMERS COLOPLAST AS (DK) 2017-08-09 EP disclosed
WO-2011160639-A1 SKIN-FRIENDLY ADHESIVES FROM POLYALKYLETHER-BASED PHOTOINITIATORS COLOPLAST A/S (DK) 2011-12-29 WO disclosed
WO-2011160637-A2 POLYURETHANE BASED PHOTOINITIATORS COLOPLAST A/S (DK) 2011-12-29 WO disclosed
WO-2011103878-A1 POLYMERIC PHOTOINITIATORS COLOPLAST A/S (DK) 2011-09-01 WO disclosed
WO-2011012137-A2 A MEDICAL DEVICE OF POLYOLEFIN COLOPLAST A/S (DK) 2011-02-03 WO disclosed
US-20100119833-A1 PHOTO-CURING OF THERMOPLASTIC COATINGS MADSEN NIELS JORGEN 2010-05-13 US disclosed
US-20100049146-A1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS COLOPLAST A/S (DK) 2010-02-25 US disclosed
EP-2104523-A1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS Coloplast A/S (DK) 2009-09-30 EP disclosed
EP-2049172-A2 PHOTO-CURING OF THERMOPLASTIC COATINGS Coloplast A/S (DK) 2009-04-22 EP disclosed
WO-2008071796-A1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS COLOPLAST A/S (DK) 2008-06-19 WO disclosed
WO-2008012325-A2 PHOTO-CURING OF THERMOPLASTIC COATINGS COLOPLAST A/S (DK) 2008-01-31 WO disclosed