SCHEMBL50851

SCHEMBL50851

CSc1ccccc1C(=O)N1CCOCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 1.00
HTT P42858 4/20 0.72
KMT2A Q03164 5/20 0.63
MEN1 O00255 4/20 0.63
SMN1; SMN2 Q16637 2/20 0.63
LMNA P02545 2/20 0.60
GAA P10253 1/20 0.57
MAPK1 P28482 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
TSHR P16473 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8806221 0.87 ALDH1A1 (0.77) ALDH1A1HTTKMT2AMEN1SMN1; SMN2
SCHEMBL7121916 0.83 SMN1; SMN2 (0.77) ALDH1A1HTTKMT2AMEN1SMN1; SMN2
SCHEMBL10013747 0.79 HTT (0.72) ALDH1A1HTTSMN1; SMN2GAANPSR1
SCHEMBL3455654 0.79 HTT (1.00) ALDH1A1HTTKMT2AMEN1SMN1; SMN2
SCHEMBL218736 0.78 ALDH1A1 (0.63) ALDH1A1HTTKMT2AMEN1SMN1; SMN2
SCHEMBL29686523 0.78 ALDH1A1 (0.63) ALDH1A1HTTKMT2AMEN1SMN1; SMN2
SCHEMBL29956307 0.78 ALDH1A1 (0.63) ALDH1A1HTTKMT2ASMN1; SMN2GAA
SCHEMBL3758627 0.78 ALDH1A1 (0.63) ALDH1A1HTTKMT2ASMN1; SMN2GAA
SCHEMBL6459112 0.77 HTT (0.67) ALDH1A1HTTKMT2AMEN1SMN1; SMN2
SCHEMBL20267430 0.77 GAA (0.73) ALDH1A1HTTKMT2AMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 311 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3685231-B1 3D PRINTING WITH POLYMERIC NANOGEL PARTICLES THE REGENTS OF THE UNIV OF COLORADO A BODY CORPORATE A COLORADO NON PROFIT (US) 2026-05-13 EP claimed
WO-2024130663-A1 DUALLY CURABLE ADHESIVE COMPOSITION HENKEL AG & CO. KGAA (DE) 2024-06-27 WO claimed
US-20240124621-A1 CURABLE COMPOSITION AND USE THEREOF HENKEL AG & CO KGAA (DE) 2024-04-18 US claimed
EP-4341354-A1 CURABLE COMPOSITION AND USE THEREOF Henkel AG & Co. KGaA (DE) 2024-03-27 EP claimed
EP-4301823-A1 CURABLE ADHESIVE COMPOSITION COMPRISING MALEIMIDE AND THIOL Henkel AG & Co. KGaA (DE) 2024-01-10 EP claimed
CN-117377731-A Curable composition and use thereof 汉高股份有限及两合公司 2024-01-09 CN claimed
US-11479620-B2 3D printing with polymeric nanogel particles THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2022-10-25 US claimed
WO-2022183481-A1 CURABLE ADHESIVE COMPOSITION COMPRISING MALEIMIDE AND THIOL HENKEL AG & CO. KGAA (DE) 2022-09-09 WO claimed
US-20200283548-A1 3D PRINTING WITH POLYMERIC NANOGEL PARTICLES THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE 2020-09-10 US claimed
US-20090220436-A1 IN SITU POLYMERIZATION FOR SKIN TREATMENT LIVING PROOF, INC. (US) 2009-09-03 US claimed
WO-2007127065-A9 IN SITU POLYMERIZATION FOR HAIR TREATMENT ANDORA INC (US) 2008-07-31 WO claimed
WO-2007134219-A2 IN SITU POLYMERIZATION FOR SKIN TREATMENT LIVING PROOF, INC. (US) 2007-11-22 WO claimed
WO-2007127065-A2 IN SITU POLYMERIZATION FOR HAIR TREATMENT LIVING PROOF, INC. (US) 2007-11-08 WO claimed
US-7226957-B1 Method for producing polymers with controlled molecular weight and end group functionality using photopolymerization in microemulsions UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2007-06-05 US claimed
WO-2005042591-A1 METHOD FOR PRODUCING POLYMERS WITH CONTROLLED MOLECULAR WEIGHT AND END GROUP FUNCTIONALITY USING PHOTOPOLYMERIZATION IN MICROEMULSIONS UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2005-05-12 WO claimed
EP-3685231-B1 3D PRINTING WITH POLYMERIC NANOGEL PARTICLES THE REGENTS OF THE UNIV OF COLORADO A BODY CORPORATE A COLORADO NON PROFIT (US) 2026-05-13 EP disclosed
US-20240425631-A1 LOW VISCOSITY URETHANE (METH)ACRYLATE MONOMERS AND THEIR USE IN PRODUCTION OF TOUGH POLYMERS WITH WELL-CONTROLLED MODULUS AND STRENGTH THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE 2024-12-26 US disclosed
EP-1308493-A2 Reversible pressure sensitive adhesives based on acrylic block copolymers tesa AG (DE) 2003-05-07 EP disclosed
EP-1251400-A2 A photopolymerizable element for use as a flexographic printing plate and a process for preparing the plate from the element E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-10-23 EP disclosed
EP-1239329-A2 A process for making a flexographic printing plate and a photosensitive element for use in the process E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-09-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090220436-A1 IN SITU POLYMERIZATION FOR SKIN TREATMENT CUTA, ESD, PFAS ALDH1A1 695/4885HTT 566/4885KMT2A 1776/4885
US-20240425631-A1 LOW VISCOSITY URETHANE (METH)ACRYLATE MONOMERS AND THEIR USE IN PRODUCTION OF TOUGH POLYMERS WITH WELL-CONTROLLED MODULUS AND STRENGTH PUF60, ACR, UMPS ALDH1A1 1480/4885HTT 128/4885KMT2A 1439/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.