SCHEMBL44792

SCHEMBL44792

C=CC(C(=O)c1sccc1C)N1CCOCC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.48
ALDH1A1 P00352 5/20 0.48
GLA P06280 1/20 0.48
PKM P14618 2/20 0.40
NPC1 O15118 3/20 0.38
RAB9A P51151 3/20 0.38
TP53 P04637 1/20 0.38
HPGD P15428 1/20 0.38
NFKB1 P19838 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
MAPK1 P28482 2/20 0.38
POLB P06746 1/20 0.38
GSK3B P49841 1/20 0.37
LMNA P02545 1/20 0.37
CYP1A2 P05177 1/20 0.36
MAPT P10636 1/20 0.36
TSHR P16473 1/20 0.36
HTT P42858 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL324878 0.73 ALDH1A1 (0.63) SMN1; SMN2ALDH1A1GLARAB9AHPGD
SCHEMBL2013741 0.70 ALDH1A1 (0.52) SMN1; SMN2ALDH1A1GLAPKMNPC1
SCHEMBL30484626 0.69 ALDH1A1 (0.52) SMN1; SMN2ALDH1A1GLANPC1RAB9A
SCHEMBL1502272 0.68 HSD17B10 (0.41) SMN1; SMN2ALDH1A1RAB9AHPGDMAPK1
SCHEMBL44791 0.68 ALDH1A1 (0.58) SMN1; SMN2ALDH1A1RAB9APOLBLMNA
SCHEMBL44793 0.68 ALDH1A1 (0.50) SMN1; SMN2ALDH1A1GLAPKMNPC1
SCHEMBL28838519 0.67 LMNA (0.51) SMN1; SMN2ALDH1A1RAB9AHPGDPOLB
SCHEMBL8019031 0.66 GSK3B (0.53) SMN1; SMN2PKMNPC1RAB9AHPGD
SCHEMBL11457979 0.65 GSK3B (0.56) SMN1; SMN2PKMNPC1RAB9AHPGD
SCHEMBL13162015 0.64 NPC1 (0.55) SMN1; SMN2ALDH1A1PKMNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109071976-B Radiation curable ink formulations 富林特集团瑞典有限公司 2022-06-03 CN disclosed
US-10252291-B2 Photo-curing of thermoplastic coatings COLOPLAST A/S (DK) 2019-04-09 US disclosed
EP-2850112-B1 NOVEL POLYMERIC PHOTOINITIATORS AND PHOTOINITIATOR MONOMERS COLOPLAST AS (DK) 2018-11-21 EP disclosed
EP-2850111-B1 NOVEL POLYMERIC PHOTOINITIATORS AND PHOTOINITIATOR MONOMERS COLOPLAST AS (DK) 2018-11-21 EP disclosed
EP-3369751-A1 NOVEL PHOTOINITIATORS Coloplast A/S (DK) 2018-09-05 EP disclosed
US-10040902-B2 Polymeric photoinitiators COLOPLAST A/S (DK) 2018-08-07 US disclosed
EP-2394676-B1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITIATOR-CONTAINING SCAFFOLDS COLOPLAST AS (DK) 2018-03-28 EP disclosed
EP-2638076-B1 NOVEL PHOTOINITIATORS COLOPLAST AS (DK) 2018-03-28 EP disclosed
EP-2585494-B1 HYDROPHILIC GELS FROM POLYALKYLETHER-BASED PHOTOINITIATORS COLOPLAST AS (DK) 2017-08-09 EP disclosed
EP-2850113-B1 NOVEL POLYMERIC PHOTOINITIATORS AND PHOTOINITIATOR MONOMERS COLOPLAST AS (DK) 2017-08-09 EP disclosed
WO-2011160639-A1 SKIN-FRIENDLY ADHESIVES FROM POLYALKYLETHER-BASED PHOTOINITIATORS COLOPLAST A/S (DK) 2011-12-29 WO disclosed
WO-2011160637-A2 POLYURETHANE BASED PHOTOINITIATORS COLOPLAST A/S (DK) 2011-12-29 WO disclosed
WO-2011103878-A1 POLYMERIC PHOTOINITIATORS COLOPLAST A/S (DK) 2011-09-01 WO disclosed
WO-2011012137-A2 A MEDICAL DEVICE OF POLYOLEFIN COLOPLAST A/S (DK) 2011-02-03 WO disclosed
US-20100119833-A1 PHOTO-CURING OF THERMOPLASTIC COATINGS MADSEN NIELS JORGEN 2010-05-13 US disclosed
US-20100049146-A1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS COLOPLAST A/S (DK) 2010-02-25 US disclosed
EP-2104523-A1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS Coloplast A/S (DK) 2009-09-30 EP disclosed
EP-2049172-A2 PHOTO-CURING OF THERMOPLASTIC COATINGS Coloplast A/S (DK) 2009-04-22 EP disclosed
WO-2008071796-A1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS COLOPLAST A/S (DK) 2008-06-19 WO disclosed
WO-2008012325-A2 PHOTO-CURING OF THERMOPLASTIC COATINGS COLOPLAST A/S (DK) 2008-01-31 WO disclosed