Thioxanthene

Thioxanthene

SCHEMBL3387198

C=CC(C(=O)c1ccccc1SC)N1CCOCC1.c1ccc2c(c1)Cc1ccccc1S2

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
KMT2A Q03164 2/20 0.37
HTT P42858 3/20 0.36
TSHR P16473 3/20 0.36
BCHE P06276 1/20 0.34
RECQL P46063 1/20 0.34
SMN1; SMN2 Q16637 3/20 0.33
MAPT P10636 2/20 0.33
POLB P06746 2/20 0.33
RAB9A P51151 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL44791 0.88 ALDH1A1 (0.58) ALDH1A1KMT2AHTTTSHRRECQL
SCHEMBL6148679 0.73 ALDH1A1 (0.62) ALDH1A1KMT2AHTTTSHRSMN1; SMN2
SCHEMBL31467399 0.73 ALDH1A1 (0.62) ALDH1A1KMT2AHTTTSHRSMN1; SMN2
SCHEMBL30484626 0.67 ALDH1A1 (0.52) ALDH1A1KMT2AHTTTSHRSMN1; SMN2
SCHEMBL50851 0.65 ALDH1A1 (1.00) ALDH1A1KMT2AHTTTSHRSMN1; SMN2
SCHEMBL8901445 0.62 ALDH1A1 (0.53) ALDH1A1KMT2AHTTTSHRRECQL
SCHEMBL29686523 0.62 ALDH1A1 (0.63) ALDH1A1KMT2AHTTTSHRRECQL
SCHEMBL218736 0.62 ALDH1A1 (0.63) ALDH1A1KMT2AHTTTSHRRECQL
SCHEMBL44792 0.62 SMN1; SMN2 (0.48) ALDH1A1HTTTSHRSMN1; SMN2MAPT
SCHEMBL27725631 0.61 ALDH1A1 (0.41) ALDH1A1KMT2AHTTBCHEMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3445826-B1 RADIATION CURABLE INK FORMULATION FLINT GROUP GERMANY GMBH (DE) 2021-07-14 EP disclosed
US-20190106583-A1 RADIATION CURABLE INK FORMULATION FLINT GROUP SWEDEN AB (SE) 2019-04-11 US disclosed
US-10252291-B2 Photo-curing of thermoplastic coatings COLOPLAST A/S (DK) 2019-04-09 US disclosed
US-10040893-B2 Polymeric photoinitiators and photoinitiator monomers COLOPLAST A/S (DK) 2018-08-07 US disclosed
US-10011688-B2 Hydrophilic gels derived from grafted photoinitiators COLOPLAST A/S (DK) 2018-07-03 US disclosed
WO-2017182638-A1 RADIATION CURABLE INK FORMULATION FLINT GROUP GERMANY GMBH (DE) 2017-10-26 WO disclosed
US-9708425-B2 Routes to polyacrylates COLOPLAST A/S (DK) 2017-07-18 US disclosed
US-9670373-B2 Polymers comprising photoinitiator moieties and dye moieties LAMBSON LIMITED (GB) 2017-06-06 US disclosed
US-9464143-B2 Grafted photoinitiators COLOPLAST A/S (DK) 2016-10-11 US disclosed
US-9399633-B2 Photoinitiators COLOPLAST A/S (DK) 2016-07-26 US disclosed
US-20130096221-A1 HYDROPHILIC GELS DERIVED FROM GRAFTED PHOTOINITIATORS COLOPLAST A/S (DK) 2013-04-18 US disclosed
US-20130096220-A1 GRAFTED PHOTOINITIATORS COLOPLAST A/S (DK) 2013-04-18 US disclosed
US-20130096224-A1 POLYURETHANE BASED PHOTOINITIATORS COLOPLAST A/S (DK) 2013-04-18 US disclosed
US-20130089581-A1 SKIN-FRIENDLY ADHESIVES FROM POLYALKLETHER-BASED PHOTOINITIATORS COLOPLAST A/S (DK) 2013-04-11 US disclosed
US-20130089582-A1 HYDROPHILIC GELS FROM POLYURETHANE-BASED PHOTOINITIATORS COLOPLAST A/S (DK) 2013-04-11 US disclosed
US-20130090406-A1 HYDROPHILIC GELS FROM POLYALKYLETHER-BASED PHOTOINITIATORS COLOPLAST A/S (DK) 2013-04-11 US disclosed
US-20130059940-A1 POLYMERIC PHOTOINITIATORS COLOPLAST A/S (DK) 2013-03-07 US disclosed
US-20120121919-A1 MEDICAL DEVICE OF POLYOLEFIN COLOPLAST A/S (DK) 2012-05-17 US disclosed
US-20100119833-A1 PHOTO-CURING OF THERMOPLASTIC COATINGS MADSEN NIELS JORGEN 2010-05-13 US disclosed
US-20100049146-A1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS COLOPLAST A/S (DK) 2010-02-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10040893-B2 Polymeric photoinitiators and photoinitiator monomers ACMSD, AAAS, PPOX ALDH1A1 1556/4885KMT2A 463/4885HTT 282/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.