SCHEMBL448011

SCHEMBL448011

OC(CCc1ccccc1)Cc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.56
MMP2 P08253 1/20 0.50
MMP9 P14780 1/20 0.50
MMP12 P39900 1/20 0.50
MMP13 P45452 1/20 0.50
MMP14 P50281 1/20 0.50
DPP4 P27487 1/20 0.50
TRPV1 Q8NER1 1/20 0.49
KEAP1 Q14145 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ANPEP P15144 2/20 0.46
ERAP1 Q9NZ08 2/20 0.46
ERAP2 Q6P179 1/20 0.46
CYP1A2 P05177 1/20 0.45
MME P08473 1/20 0.45
PPARG P37231 3/20 0.44
PPARA Q07869 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL145170 0.90 TRPV1 (0.62) TRPA1MMP2MMP9MMP12MMP13
SCHEMBL4799370 0.88 MMP2 (0.55) TRPA1MMP2MMP9MMP12MMP13
SCHEMBL5105980 0.88 TRPA1 (0.52) TRPA1TRPV1CYP1A2
Hydrochloric Acid SCHEMBL9848365 0.88 TRPA1 (0.50) TRPA1MMP2MMP9MMP12MMP13
SCHEMBL9556315 0.87 TRPA1 (0.53) TRPA1TRPV1PPARGPPARA
SCHEMBL7166933 0.85 TRPA1 (0.58) TRPA1TRPV1PPARGPPARA
SCHEMBL5097040 0.84 TRPA1 (0.48) TRPA1TRPV1CYP1A2
SCHEMBL1833635 0.83 TRPA1 (0.55) TRPA1TRPV1CYP1A2
SCHEMBL2074517 0.82 TDP1 (0.52) MMP2MMP9MMP12MMP13MMP14
SCHEMBL5868422 0.82 TRPA1 (0.47) TRPA1TRPV1TDP1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2463374-A2 Isolated alcohol dehydrogenase enzymes and uses thereof Bio Architecture Lab, Inc. (US) 2012-06-13 EP claimed
US-20090155873-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-18 US claimed
US-20090139134-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-04 US claimed
EP-3230463-B2 RAPID PRETREATMENT APALTA PATENTS OUE (EE) 2025-07-16 EP disclosed
US-20240425893-A1 RAPID PRETREATMENT Apalta Patents OÜ (EE) 2024-12-26 US disclosed
US-12054761-B2 Rapid pretreatment Apalta Patents OÜ (EE) 2024-08-06 US disclosed
US-11821047-B2 High pressure zone formation for pretreatment Apalta Patent OÜ (EE) 2023-11-21 US disclosed
US-20230295678-A1 RAPID PRETREATMENT Apalta Patents OÜ (EE) 2023-09-21 US disclosed
EP-4098750-A1 RAPID PRETREATMENT Sweetwater Energy, Inc. (US) 2022-12-07 EP disclosed
EP-3230463-B1 RAPID PRETREATMENT SWEETWATER ENERGY INC (US) 2022-05-25 EP disclosed
US-11332723-B2 Engineered microorganisms for production of commodity chemicals and cellular biomass THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-05-17 US disclosed
US-20100086981-A1 COMPOSITIONS AND METHODS FOR IMPROVED SACCHARIFICATION OF BIOMASS QTEROS, INC. (US) 2010-04-08 US disclosed
US-20090203089-A1 ISOLATED ALCOHOL DEHYDROGENASE ENZYMES AND USES THEREOF BIO ARCHITECTURE LAB, INC. (US) 2009-08-13 US disclosed
US-20090155873-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-18 US disclosed
US-20090139134-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-04 US disclosed
WO-2009046375-A2 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-04-09 WO disclosed
WO-2009046370-A2 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-04-09 WO disclosed
US-4723008-A VIRICIDES NISSHIN FLOUR MILLING CO., LTD. (JP) 1988-02-02 US disclosed
US-4700002-A VIRICIDES; INTERFERON INDUCERS NISSHIN FLOUR MILLING CO., LTD. (JP) 1987-10-13 US disclosed
US-4658063-A Isoprenylamine derivatives NISSHIN FLOUR MILLING CO., LTD. (JP) 1987-04-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090139134-A1 BIOFUEL PRODUCTION MGAM, DCXR, MANBA TRPA1 3765/4885MMP2 360/4885MMP9 728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.