SCHEMBL4480555

SCHEMBL4480555

CCCCN(c1cccc(NC2CCCCC2)c1)C1CCCCC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ICMT O60725 1/20 0.39
ALB P02768 1/20 0.39
TRPV1 Q8NER1 1/20 0.37
KDM4E B2RXH2 2/20 0.37
MC4R P32245 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.35
BCHE P06276 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
PGR P06401 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
GFER P55789 1/20 0.34
HSD17B10 Q99714 1/20 0.34
EPHX1 P07099 1/20 0.34
EPHX2 P34913 1/20 0.34
CNR1 P21554 1/20 0.34
CNR2 P34972 1/20 0.34
POLB P06746 1/20 0.33
HSD11B1 P28845 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4476457 0.96 ICMT (0.43) ICMTALBTRPV1KDM4EMC4R
SCHEMBL4493879 0.85 BCHE (0.40) TRPV1KDM4EMC4RSMN1; SMN2BCHE
SCHEMBL4489491 0.84 TRPV1 (0.40) ICMTALBTRPV1KDM4EMC4R
SCHEMBL4476492 0.83 MC4R (0.44) ICMTALBTRPV1KDM4EMC4R
SCHEMBL4497068 0.81 IDO1 (0.37) KDM4ESMN1; SMN2MEN1KMT2ANPC1
SCHEMBL4477077 0.81 MC4R (0.41) ICMTALBTRPV1KDM4EMC4R
SCHEMBL11690784 0.78 DRD2 (0.51) TRPV1KDM4EMC4RSMN1; SMN2BCHE
SCHEMBL9781532 0.77 DRD3 (0.43) MC4RDRD2OPRM1DRD3OPRK1
SCHEMBL9214632 0.77 DRD3 (0.43) MC4RDRD2OPRM1DRD3OPRK1
SCHEMBL9214764 0.77 DRD3 (0.43) MC4RDRD2OPRM1DRD3OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090156441-A1 Cycloalkyl phenylenediamines as deposit control agents for lubricants GREAT LAKES CHEMICAL GLOBAL, INC. 2009-06-18 US claimed
US-20090156441-A1 Cycloalkyl phenylenediamines as deposit control agents for lubricants GREAT LAKES CHEMICAL GLOBAL, INC. 2009-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090156441-A1 Cycloalkyl phenylenediamines as deposit control agents for lubricants C5, C9, C1S ICMT 1464/4885ALB 1483/4885TRPV1 3899/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.