Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | ICMT | O60725 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4489491 | 0.96 | TRPV1 (0.40) | MC4REPHX1EPHX2ICMTALB | |
| SCHEMBL4496003 | 0.89 | MC4R (0.44) | MC4RICMTALBTRPV1CNR2 | |
| SCHEMBL4476457 | 0.85 | ICMT (0.43) | MC4REPHX1EPHX2ICMTALB | |
| SCHEMBL4483045 | 0.84 | LMNA (0.41) | EPHX1TRPV1CNR2MAPTLMNA | |
| SCHEMBL4474179 | 0.83 | MC4R (0.41) | MC4RICMTALBTRPV1CNR2 | |
| SCHEMBL4471201 | 0.82 | TRPV1 (0.41) | MC4RTRPV1CNR2THRATHRB | |
| SCHEMBL9781490 | 0.82 | CNR2 (0.43) | MC4RICMTALBTRPV1CNR2 | |
| SCHEMBL7532689 | 0.81 | MC4R (0.53) | MC4RICMTALBTRPV1CNR2 | |
| SCHEMBL14288494 | 0.81 | MC4R (0.53) | MC4RICMTALBTRPV1CNR2 | |
| SCHEMBL4480555 | 0.81 | ICMT (0.39) | MC4REPHX1EPHX2ICMTALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156441-A1 | Cycloalkyl phenylenediamines as deposit control agents for lubricants | GREAT LAKES CHEMICAL GLOBAL, INC. | 2009-06-18 | — | — | US | claimed |
| US-20090156441-A1 | Cycloalkyl phenylenediamines as deposit control agents for lubricants | GREAT LAKES CHEMICAL GLOBAL, INC. | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156441-A1 | Cycloalkyl phenylenediamines as deposit control agents for lubricants | C5, C9, C1S | MC4R 3325/4885EPHX1 1205/4885EPHX2 1292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.