Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 4/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4482455 | 0.76 | ELANE (0.42) | L3MBTL1CYP2C9CYP2C19NPSR1ELANE | |
| SCHEMBL4455507 | 0.69 | GAA (0.50) | L3MBTL1GAAELANECTSGPRTN3 | |
| SCHEMBL4322743 | 0.68 | CYP2C9 (0.38) | GAACYP2C9CYP2C19NPSR1ELANE | |
| SCHEMBL28674345 | 0.64 | LTA4H (0.38) | L3MBTL1CYP2C9CYP2C19NPSR1ELANE | |
| SCHEMBL28674344 | 0.63 | MMP1 (0.38) | L3MBTL1GAACYP2C9CYP2C19NPSR1 | |
| SCHEMBL6553757 | 0.61 | MEN1 (0.43) | L3MBTL1CYP2C9CYP2C19ELANETDP1 | |
| SCHEMBL8105297 | 0.58 | TP53 (0.41) | NPSR1ELANEMMP2MMP9MMP8 | |
| SCHEMBL1587776 | 0.58 | ELANE (0.42) | L3MBTL1GAANPSR1ELANECTSG | |
| SCHEMBL28382522 | 0.58 | CYP2C9 (0.50) | L3MBTL1CYP2C9CYP2C19NPSR1TDP1 | |
| SCHEMBL16174713 | 0.57 | ELANE (0.44) | L3MBTL1GAACYP2C9CYP2C19ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090137577-A1 | HETEROCYCLIC COMPOUNDS | PFIZER INC. | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137577-A1 | HETEROCYCLIC COMPOUNDS | CYP2D6, ABCG2, CYP2B6 | L3MBTL1 4751/4885GAA 121/4885CYP2C9 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.