Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 11/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 4/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4484957 | 1.00 | DPP4 (0.44) | DPP4DPP7FAAHCYP3A4CYP2D6 | |
| Trifluoroacetic Acid SCHEMBL6381459 | 0.85 | DPP7 (0.39) | DPP4DPP7DPP9DPP8KCNH2 | |
| Trifluoroacetic Acid SCHEMBL6381462 | 0.85 | DPP7 (0.39) | DPP4DPP7DPP9DPP8KCNH2 | |
| SCHEMBL4483103 | 0.73 | CTSK (0.46) | DPP4DPP7FAAHCYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL4480328 | 0.70 | KMT2A (0.59) | DPP4DPP7FAAHCYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL5943207 | 0.68 | SMN1; SMN2 (0.54) | DPP4DPP7FAAHCYP3A4CYP2D6 | |
| SCHEMBL26330809 | 0.64 | ALDH1A1 (0.52) | TSHRMEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10936662 | 0.61 | KMT2A (0.62) | FAAHCYP3A4CYP2D6TSHRALOX12 | |
| SCHEMBL14412954 | 0.61 | EPHX2 (0.62) | FAAHCYP3A4CYP2D6TSHRALOX12 | |
| SCHEMBL5943227 | 0.61 | ALDH1A1 (0.46) | FAAHCYP3A4CYP2D6TSHRALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622487-B2 | Piperidine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |
| US-20060167052-A1 | Piperidine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-07-27 | — | — | US | disclosed |
| EP-1553084-A1 | PIPERIDINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Pharmaceutical Company Limited (JP) | 2005-07-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167052-A1 | Piperidine derivative, process for producing the same, and use | OPRL1, OXTR, OPRM1 | DPP4 3999/4885DPP7 3767/4885FAAH 447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.